Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHISA7
  • Mouse genes Shisa7
  • Rat genes Shisa7
  • Zfish genes shisa7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shisa7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050811	GABA receptor binding	Shisa7	IDA		Mouse	MGI:MGI:6377643|PMID:31601770
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Shisa7	IDA		Mouse	MGI:MGI:6110888|PMID:29199957
Molecular Function	GO:0005515	protein binding	Shisa7	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:6110888|PMID:29199957
Cellular Component	GO:0098985	asymmetric, glutamatergic, excitatory synapse	Shisa7	IDA		Mouse	MGI:MGI:6110888|PMID:29199957
Cellular Component	GO:0098978	glutamatergic synapse	Shisa7	IEP		Mouse	PMID:29199957
Cellular Component	GO:0098978	glutamatergic synapse	Shisa7	IDA		Mouse	PMID:29199957
Cellular Component	GO:0098978	glutamatergic synapse	Shisa7	IPI		Mouse	PMID:29199957
Cellular Component	GO:0098978	glutamatergic synapse	Shisa7	IMP		Mouse	PMID:29199957
Cellular Component	GO:0014069	postsynaptic density	Shisa7	IDA		Mouse	MGI:MGI:6110888|PMID:29199957
Cellular Component	GO:0099634	postsynaptic specialization membrane	Shisa7	IDA		Mouse	PMID:29199957
Cellular Component	GO:0099634	postsynaptic specialization membrane	Shisa7	IPI		Mouse	PMID:29199957
Cellular Component	GO:0099634	postsynaptic specialization membrane	Shisa7	IEP		Mouse	PMID:29199957
Cellular Component	GO:0099634	postsynaptic specialization membrane	Shisa7	IMP		Mouse	PMID:29199957
Biological Process	GO:0097112	gamma-aminobutyric acid receptor clustering	Shisa7	IDA		Mouse	MGI:MGI:6377643|PMID:31601770
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Shisa7	IDA		Mouse	MGI:MGI:6377643|PMID:31601770
Biological Process	GO:0007613	memory	Shisa7	IMP		Mouse	MGI:MGI:6110888|PMID:29199957
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Shisa7	IMP		Mouse	MGI:MGI:6110888|PMID:29199957
Biological Process	GO:1904717	regulation of AMPA glutamate receptor clustering	Shisa7	IMP		Mouse	MGI:MGI:6110888|PMID:29199957
Biological Process	GO:0106040	regulation of GABA-A receptor activity	Shisa7	IDA		Mouse	MGI:MGI:6377643|PMID:31601770
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Shisa7	IMP		Mouse	PMID:29199957
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Shisa7	IDA		Mouse	PMID:29199957
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Shisa7	IPI		Mouse	PMID:29199957

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern