Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SGMS2
  • Mouse genes Sgms2
  • Rat genes Sgms2
  • Zfish genes sgms2a,sgms2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sgms2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047493	ceramide cholinephosphotransferase activity	SGMS2	IDA		Human	PMID:14685263
Molecular Function	GO:0002950	ceramide phosphoethanolamine synthase activity	Sgms2	IMP		Mouse	PMID:25667419
Molecular Function	GO:0002950	ceramide phosphoethanolamine synthase activity	Sgms2	IMP	MGI:MGI:4818459	Mouse	PMID:25605874
Molecular Function	GO:0005515	protein binding	SGMS2	IPI	UniProtKB:O95159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SGMS2	IPI	UniProtKB:P23763-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SGMS2	IPI	UniProtKB:Q59EV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SGMS2	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SGMS2	IPI	UniProtKB:Q9UBY5	Human	PMID:32296183
Molecular Function	GO:0033188	sphingomyelin synthase activity	SGMS2	IDA		Human	PMID:17982138
Molecular Function	GO:0033188	sphingomyelin synthase activity	SGMS2	IDA		Human	PMID:30779713
Molecular Function	GO:0033188	sphingomyelin synthase activity	Sgms2	IDA		Mouse	MGI:MGI:6221394|PMID:27892528
Molecular Function	GO:0033188	sphingomyelin synthase activity	Sgms2	IMP		Mouse	PMID:25667419
Cellular Component	GO:0005794	Golgi apparatus	SGMS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	SGMS2	IDA		Human	PMID:14685263
Cellular Component	GO:0000139	Golgi membrane	SGMS2	IDA		Human	PMID:14685263
Cellular Component	GO:0005654	nucleoplasm	SGMS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SGMS2	IDA		Human	PMID:14685263
Cellular Component	GO:0005886	plasma membrane	SGMS2	IDA		Human	PMID:30779713
Cellular Component	GO:0005886	plasma membrane	Sgms2	IDA		Rat	PMID:17210739|RGD:8553673
Biological Process	GO:0046513	ceramide biosynthetic process	Sgms2	IMP	MGI:MGI:4818459	Mouse	PMID:25605874
Biological Process	GO:1905373	ceramide phosphoethanolamine biosynthetic process	Sgms2	IMP		Mouse	PMID:25667419
Biological Process	GO:0030500	regulation of bone mineralization	SGMS2	IMP		Human	PMID:30779713
Biological Process	GO:0006686	sphingomyelin biosynthetic process	SGMS2	IDA		Human	PMID:14685263
Biological Process	GO:0006686	sphingomyelin biosynthetic process	SGMS2	IDA		Human	PMID:17982138
Biological Process	GO:0006686	sphingomyelin biosynthetic process	Sgms2	IMP		Mouse	MGI:MGI:6221394|PMID:27892528
Biological Process	GO:0006686	sphingomyelin biosynthetic process	Sgms2	IMP		Mouse	PMID:25667419

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern