Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SFXN1
  • Mouse genes Sfxn1
  • Rat genes Sfxn1
  • Zfish genes sfxn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sfxn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015180	L-alanine transmembrane transporter activity	SFXN1	IDA		Human	PMID:30442778
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	SFXN1	IDA		Human	PMID:30442778
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:O60669	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q15546	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFXN1	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Cellular Component	GO:0005743	mitochondrial inner membrane	SFXN1	IDA		Human	PMID:30442778
Cellular Component	GO:0005743	mitochondrial inner membrane	Sfxn1	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005739	mitochondrion	SFXN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Sfxn1	IDA		Mouse	PMID:11274051
Cellular Component	GO:0005739	mitochondrion	Sfxn1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Sfxn1	HDA		Mouse	PMID:18614015
Biological Process	GO:0030218	erythrocyte differentiation	Sfxn1	IMP	MGI:MGI:1856864	Mouse	PMID:11274051
Biological Process	GO:0042541	hemoglobin biosynthetic process	sfxn1	IMP	ZFIN:ZDB-MRPHLNO-211206-3	Zfish	PMID:33524530
Biological Process	GO:0042541	hemoglobin biosynthetic process	sfxn1	IMP	ZFIN:ZDB-GENO-220824-1	Zfish	PMID:33524530
Biological Process	GO:0006826	iron ion transport	Sfxn1	IMP	MGI:MGI:1856864	Mouse	PMID:11274051
Biological Process	GO:0015808	L-alanine transport	SFXN1	IDA		Human	PMID:30442778
Biological Process	GO:0015825	L-serine transport	SFXN1	IDA		Human	PMID:30442778
Biological Process	GO:0043362	nucleate erythrocyte maturation	sfxn1	IMP	ZFIN:ZDB-GENO-220824-1	Zfish	PMID:33524530
Biological Process	GO:0043362	nucleate erythrocyte maturation	sfxn1	IMP	ZFIN:ZDB-MRPHLNO-211206-3	Zfish	PMID:33524530
Biological Process	GO:0006730	one-carbon metabolic process	SFXN1	IDA		Human	PMID:30442778
Biological Process	GO:0140300	serine import into mitochondrion	SFXN1	IDA		Human	PMID:30442778

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern