Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETD7
  • Mouse genes Setd7
  • Rat genes Setd7
  • Zfish genes setd7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setd7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Setd7	IDA		Rat	PMID:20930066|RGD:9491847
Molecular Function	GO:0140938	histone H3 methyltransferase activity	SETD7	IDA		Human	PMID:16415881
Molecular Function	GO:0042054	histone methyltransferase activity	SETD7	IDA		Human	PMID:17707234
Molecular Function	GO:0002039	p53 binding	SETD7	IPI	UniProtKB:P04637	Human	PMID:17108971
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P68431	Human	PMID:12540855
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P04637	Human	PMID:15525938
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P68433	Human	PMID:15525938
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P04637	Human	PMID:16415881
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:Q12962	Human	PMID:16415881
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P04637	Human	PMID:17108971
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P04637	Human	PMID:17805299
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:Q04206	Human	PMID:19262565
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P26358	Human	PMID:19282482
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:Q04206	Human	PMID:19864627
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P06400	Human	PMID:21119616
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:Q04207	Human	PMID:21131967
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P26358	Human	PMID:21151116
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P04637	Human	PMID:21245319
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:Q96EB6	Human	PMID:21245319
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:P04637	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:Q9UHV2	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:Q96RI1	Human	PMID:22345554
Molecular Function	GO:0005515	protein binding	SETD7	IPI	UniProtKB:Q9WVH4	Human	PMID:22402663
Molecular Function	GO:0005515	protein binding	Setd7	IPI	PR:O54864	Mouse	PMID:23509280
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	SETD7	IDA		Human	PMID:16415881
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	SETD7	IDA		Human	PMID:17108971
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	SETD7	IDA		Human	PMID:35210392
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	Setd7	IDA		Mouse	PMID:27292644
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	Setd7	IDA		Mouse	PMID:35210392
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	Setd7	IDA		Mouse	PMID:23509280
Cellular Component	GO:0005694	chromosome	SETD7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	SETD7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Setd7	IDA		Rat	PMID:20930066|RGD:9491847
Biological Process	GO:0006325	chromatin organization	Setd7	IDA		Mouse	PMID:23509280
Biological Process	GO:0006974	DNA damage response	SETD7	IDA		Human	PMID:23509280
Biological Process	GO:0003007	heart morphogenesis	setd7	IMP	ZFIN:ZDB-MRPHLNO-151013-6	Zfish	PMID:25997738
Biological Process	GO:0003007	heart morphogenesis	setd7	IGI	ZFIN:ZDB-MRPHLNO-151013-5,ZFIN:ZDB-MRPHLNO-151013-6	Zfish	PMID:25997738
Biological Process	GO:0070828	heterochromatin organization	SETD7	IDA		Human	PMID:23509280
Biological Process	GO:0070828	heterochromatin organization	Setd7	IMP		Mouse	PMID:23509280
Biological Process	GO:0051348	negative regulation of transferase activity	Setd7	IDA		Mouse	PMID:23509280
Biological Process	GO:0018027	peptidyl-lysine dimethylation	SETD7	IDA		Human	PMID:17108971
Biological Process	GO:0018022	peptidyl-lysine methylation	Setd7	IDA		Mouse	PMID:35210392
Biological Process	GO:0018022	peptidyl-lysine methylation	Setd7	IDA		Mouse	PMID:23509280
Biological Process	GO:0018026	peptidyl-lysine monomethylation	SETD7	IDA		Human	PMID:17108971
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Setd7	IMP		Rat	PMID:20930066|RGD:9491847
Biological Process	GO:0006479	protein methylation	Setd7	IDA		Mouse	PMID:27292644
Biological Process	GO:0045471	response to ethanol	Setd7	IEP		Rat	PMID:23413810|RGD:9491848

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern