Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETD6
  • Mouse genes Setd6
  • Rat genes Setd6
  • Zfish genes setd6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setd6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051059	NF-kappaB binding	SETD6	IPI	UniProtKB:Q04207	Human	PMID:21131967
Molecular Function	GO:0005515	protein binding	SETD6	IPI	UniProtKB:Q04207	Human	PMID:21131967
Molecular Function	GO:0005515	protein binding	Setd6	IPI	UniProtKB:Q9UHL9	Mouse	MGI:MGI:5887186|PMID:26275350
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	SETD6	IDA		Human	PMID:21131967
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	SETD6	IDA		Human	PMID:21515635
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	SETD6	IDA		Human	PMID:23324626
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	SETD6	IDA		Human	PMID:30189201
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	SETD6	IDA		Human	PMID:21515635
Cellular Component	GO:0005829	cytosol	SETD6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SETD6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SETD6	IDA		Human	PMID:21131967
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	SETD6	IMP		Human	PMID:21131967
Biological Process	GO:0018026	peptidyl-lysine monomethylation	SETD6	IDA		Human	PMID:21131967
Biological Process	GO:0018026	peptidyl-lysine monomethylation	SETD6	IDA		Human	PMID:21515635
Biological Process	GO:0018026	peptidyl-lysine monomethylation	SETD6	IDA		Human	PMID:30189201
Biological Process	GO:0050727	regulation of inflammatory response	SETD6	IMP		Human	PMID:21131967
Biological Process	GO:0048863	stem cell differentiation	Setd6	IDA		Mouse	MGI:MGI:5689089|PMID:23324626
Biological Process	GO:0019827	stem cell population maintenance	Setd6	IDA		Mouse	MGI:MGI:5689089|PMID:23324626

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern