Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETD4
  • Mouse genes Setd4
  • Rat genes Setd4
  • Zfish genes setd4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setd4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	Setd4	IDA		Mouse	MGI:MGI:6694359|PMID:31376731
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	SETD4	IDA		Human	PMID:31308046
Cellular Component	GO:0005829	cytosol	SETD4	IDA		Human	PMID:24738023
Cellular Component	GO:0005634	nucleus	SETD4	IDA		Human	PMID:24738023
Biological Process	GO:0044648	histone H3-K4 dimethylation	Setd4	IDA		Mouse	MGI:MGI:6694359|PMID:31376731
Biological Process	GO:0097692	histone H3-K4 monomethylation	Setd4	IDA		Mouse	MGI:MGI:6694359|PMID:31376731
Biological Process	GO:0050729	positive regulation of inflammatory response	Setd4	IDA		Mouse	MGI:MGI:6694359|PMID:31376731
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Setd4	IDA		Mouse	MGI:MGI:6694359|PMID:31376731
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Setd4	IDA		Mouse	MGI:MGI:6694359|PMID:31376731
Biological Process	GO:0071863	regulation of cell proliferation in bone marrow	Setd4	IMP		Mouse	MGI:MGI:6695863|PMID:33506343

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern