Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SESN3
  • Mouse genes Sesn3
  • Rat genes Sesn3
  • Zfish genes sesn3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sesn3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SESN3	IPI	UniProtKB:Q96S15	Human	PMID:25263562
Molecular Function	GO:0005515	protein binding	SESN3	IPI	UniProtKB:Q96S15	Human	PMID:26449471
Molecular Function	GO:0005515	protein binding	Sesn3	IPI	UniProtKB:Q6QI06	Mouse	MGI:MGI:5779633|PMID:25377878
Molecular Function	GO:0005515	protein binding	Sesn3	IPI	UniProtKB:Q5VZM2,UniProtKB:Q7L523,UniProtKB:Q9HB90,UniProtKB:Q9NQL2	Mouse	MGI:MGI:5604284|PMID:25259925
Cellular Component	GO:0005737	cytoplasm	SESN3	IDA		Human	PMID:25263562
Cellular Component	GO:0031932	TORC2 complex	Sesn3	IDA		Mouse	MGI:MGI:5779633|PMID:25377878
Biological Process	GO:0034198	cellular response to amino acid starvation	SESN3	IMP		Human	PMID:25263562
Biological Process	GO:0071230	cellular response to amino acid stimulus	Sesn3	IMP		Mouse	MGI:MGI:5604284|PMID:25259925
Biological Process	GO:0042149	cellular response to glucose starvation	SESN3	IMP		Human	PMID:25263562
Biological Process	GO:0042593	glucose homeostasis	Sesn3	IMP		Mouse	MGI:MGI:5779633|PMID:25377878
Biological Process	GO:0042593	glucose homeostasis	Sesn3	IGI	MGI:MGI:2651874	Mouse	PMID:22958918
Biological Process	GO:0007626	locomotory behavior	sesn3	IMP	ZFIN:ZDB-MRPHLNO-160413-5,ZFIN:ZDB-MRPHLNO-160413-6	Zfish	PMID:25615886
Biological Process	GO:1904262	negative regulation of TORC1 signaling	SESN3	IMP		Human	PMID:25263562
Biological Process	GO:1904262	negative regulation of TORC1 signaling	Sesn3	IMP		Mouse	MGI:MGI:5604284|PMID:25259925
Biological Process	GO:0046626	regulation of insulin receptor signaling pathway	Sesn3	IMP		Mouse	MGI:MGI:5779633|PMID:25377878
Biological Process	GO:0051896	regulation of protein kinase B signaling	Sesn3	IDA		Mouse	PMID:22958918
Biological Process	GO:0032868	response to insulin	Sesn3	IMP		Mouse	MGI:MGI:5779633|PMID:25377878
Biological Process	GO:0032868	response to insulin	Sesn3	IGI	MGI:MGI:2651874	Mouse	PMID:22958918
Biological Process	GO:0038203	TORC2 signaling	Sesn3	IMP		Mouse	MGI:MGI:5779633|PMID:25377878

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern