Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEMA7A
  • Mouse genes Sema7a
  • Rat genes Sema7a
  • Zfish genes sema7a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sema7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	Sema7a	IPI	UniProtKB:P09055|UniProtKB:Q3V3R4	Mouse	MGI:MGI:3710037|PMID:17377534
Molecular Function	GO:0005515	protein binding	SEMA7A	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	SEMA7A	IPI	UniProtKB:O60486	Human	PMID:20727575
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SEMA7A	HDA		Human	PMID:28327460
Cellular Component	GO:0009897	external side of plasma membrane	Sema7a	IDA		Mouse	MGI:MGI:3710037|PMID:17377534
Cellular Component	GO:0016020	membrane	SEMA7A	HDA		Human	PMID:16210410
Biological Process	GO:0048675	axon extension	Sema7a	IDA		Mouse	PMID:12879062
Biological Process	GO:0048675	axon extension	Sema7a	IMP	MGI:MGI:2683867	Mouse	PMID:12879062
Biological Process	GO:0048675	axon extension	Sema7a	IGI	MGI:MGI:96610	Mouse	PMID:12879062
Biological Process	GO:0007229	integrin-mediated signaling pathway	SEMA7A	IDA		Human	PMID:12879062
Biological Process	GO:0007229	integrin-mediated signaling pathway	Sema7a	IDA		Mouse	MGI:MGI:3710037|PMID:17377534
Biological Process	GO:0031175	neuron projection development	Sema7a	IMP	MGI:MGI:2683867	Mouse	PMID:12879062
Biological Process	GO:0021988	olfactory lobe development	Sema7a	IMP	MGI:MGI:2683867	Mouse	PMID:12879062
Biological Process	GO:0021988	olfactory lobe development	Sema7a	IDA		Mouse	PMID:12879062
Biological Process	GO:0001649	osteoblast differentiation	SEMA7A	HDA		Human	PMID:16210410
Biological Process	GO:0045773	positive regulation of axon extension	SEMA7A	IDA		Human	PMID:12879062
Biological Process	GO:0045773	positive regulation of axon extension	Sema7a	IDA		Mouse	PMID:12879062
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	SEMA7A	IDA		Human	PMID:12879062
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Sema7a	IDA		Mouse	MGI:MGI:3710037|PMID:17377534
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Sema7a	IDA		Mouse	MGI:MGI:3710037|PMID:17377534
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Sema7a	IDA		Mouse	PMID:12879062
Biological Process	GO:0006468	protein phosphorylation	Sema7a	IDA		Mouse	PMID:12879062
Biological Process	GO:0050727	regulation of inflammatory response	Sema7a	IDA		Mouse	MGI:MGI:3710037|PMID:17377534

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern