Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEMA4A
  • Mouse genes Sema4a
  • Rat genes Sema4a
  • Zfish genes sema4ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sema4a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SEMA4A	IPI	UniProtKB:Q9Y4D7	Human	PMID:17318185
Biological Process	GO:0007409	axonogenesis	Sema4a	IMP		Mouse	MGI:MGI:5315684|PMID:20043131
Biological Process	GO:0016525	negative regulation of angiogenesis	Sema4a	IMP		Mouse	MGI:MGI:3703310|PMID:17318185
Biological Process	GO:1904891	positive regulation of excitatory synapse assembly	Sema4a	IMP		Mouse	MGI:MGI:6269924|PMID:29981480
Biological Process	GO:1905704	positive regulation of inhibitory synapse assembly	Sema4a	IMP		Mouse	MGI:MGI:6269924|PMID:29981480
Biological Process	GO:0008360	regulation of cell shape	Sema4a	IDA		Mouse	MGI:MGI:5315684|PMID:20043131
Biological Process	GO:0010594	regulation of endothelial cell migration	Sema4a	IMP		Mouse	MGI:MGI:3703310|PMID:17318185
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Sema4a	IDA		Mouse	MGI:MGI:5315684|PMID:20043131
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Sema4a	IMP		Mouse	MGI:MGI:3703310|PMID:17318185
Biological Process	GO:0002292	T cell differentiation involved in immune response	Sema4a	IMP		Mouse	MGI:MGI:3574161|PMID:15780988
Biological Process	GO:0045063	T-helper 1 cell differentiation	Sema4a	IMP		Mouse	MGI:MGI:3574161|PMID:15780988

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern