Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEC24A
  • Mouse genes Sec24a
  • Rat genes Sec24a
  • Zfish genes sec24a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sec24a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SEC24A	IPI	UniProtKB:O75396	Human	PMID:17499046
Molecular Function	GO:0005515	protein binding	SEC24A	IPI	UniProtKB:Q01844	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEC24A	IPI	UniProtKB:Q92734	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEC24A	IPI	UniProtKB:Q9NTJ5	Human	PMID:31806350
Molecular Function	GO:0005515	protein binding	SEC24A	IPI	UniProtKB:Q9NV64	Human	PMID:31806350
Molecular Function	GO:0005515	protein binding	SEC24A	IPI	UniProtKB:Q8IXL6	Human	PMID:34349020
Molecular Function	GO:0008270	zinc ion binding	SEC24A	IDA		Human	PMID:18843296
Cellular Component	GO:0030127	COPII vesicle coat	SEC24A	IDA		Human	PMID:17499046
Biological Process	GO:0042632	cholesterol homeostasis	Sec24a	IMP		Mouse	PMID:23580231
Biological Process	GO:0090110	COPII-coated vesicle cargo loading	SEC24A	IDA		Human	PMID:17499046
Biological Process	GO:0090110	COPII-coated vesicle cargo loading	SEC24A	IDA		Human	PMID:18843296
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	SEC24A	IMP		Human	PMID:20427317
Biological Process	GO:0050714	positive regulation of protein secretion	Sec24a	IMP		Mouse	PMID:23580231
Biological Process	GO:0032374	regulation of cholesterol transport	Sec24a	IMP		Mouse	PMID:23580231

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern