Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SDHA
  • Mouse genes Sdha
  • Rat genes Sdha
  • Zfish genes sdha
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sdha

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:Q16595	Human	PMID:15961414
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:Q9NX18	Human	PMID:19628817
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:P21912	Human	PMID:19688755
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:Q12931	Human	PMID:23747254
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:P21912	Human	PMID:24606901
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:Q9NX18	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:P21912	Human	PMID:26749241
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:P26045	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:P21912	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SDHA	IPI	UniProtKB:Q9NX18	Human	PMID:28514442
Molecular Function	GO:0008177	succinate dehydrogenase (ubiquinone) activity	SDHA	IMP		Human	PMID:24781757
Molecular Function	GO:0008177	succinate dehydrogenase (ubiquinone) activity	Sdha	IMP		Rat	PMID:16520240|RGD:2306906
Molecular Function	GO:0000104	succinate dehydrogenase activity	SDHA	IMP		Human	PMID:7550341
Cellular Component	GO:0005743	mitochondrial inner membrane	Sdha	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005743	mitochondrial inner membrane	Sdha	IDA		Rat	PMID:16520240|RGD:2306906
Cellular Component	GO:0005739	mitochondrion	SDHA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	SDHA	IDA		Human	PMID:16826196
Cellular Component	GO:0005739	mitochondrion	SDHA	IDA		Human	PMID:7550341
Cellular Component	GO:0005739	mitochondrion	Sdha	IDA		Mouse	PMID:26644517
Cellular Component	GO:0005739	mitochondrion	Sdha	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Sdha	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Sdha	IDA		Mouse	PMID:16120479
Cellular Component	GO:0005739	mitochondrion	Sdha	IDA		Mouse	PMID:19837698
Cellular Component	GO:0005739	mitochondrion	Sdha	IDA		Mouse	PMID:19808025
Cellular Component	GO:0043209	myelin sheath	Sdha	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005730	nucleolus	SDHA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045257	succinate dehydrogenase complex (ubiquinone)	Sdha	IDA		Mouse	PMID:16120479
Biological Process	GO:0007399	nervous system development	SDHA	IMP		Human	PMID:16361598
Biological Process	GO:0022904	respiratory electron transport chain	SDHA	IDA		Human	PMID:7550341
Biological Process	GO:0022904	respiratory electron transport chain	Sdha	IMP		Rat	PMID:16520240|RGD:2306906
Biological Process	GO:0006105	succinate metabolic process	SDHA	IDA		Human	PMID:7550341
Biological Process	GO:0006105	succinate metabolic process	Sdha	IMP		Rat	PMID:16520240|RGD:2306906

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern