Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCO1
  • Mouse genes Sco1
  • Rat genes Sco1
  • Zfish genes sco1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sco1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q14061	Human	PMID:18458339
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q5RI15	Human	PMID:24403053
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q5JTJ3	Human	PMID:26160915
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q5RI15	Human	PMID:28330871
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q8N8Q8	Human	PMID:28330871
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q53S58	Human	PMID:29154948
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q5RI15	Human	PMID:29154948
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q9P0S2	Human	PMID:29381136
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q14061	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCO1	IPI	UniProtKB:P21964-2	Human	PMID:32814053
Cellular Component	GO:0005743	mitochondrial inner membrane	SCO1	IDA		Human	PMID:15229189
Cellular Component	GO:0005739	mitochondrion	SCO1	IDA		Human	PMID:9878253
Cellular Component	GO:0005739	mitochondrion	Sco1	IDA		Mouse	PMID:19837698
Cellular Component	GO:0005739	mitochondrion	Sco1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0030016	myofibril	SCO1	IDA		Human	PMID:20864674
Biological Process	GO:0019371	cyclooxygenase pathway	Sco1	IMP	MGI:MGI:2182095,MGI:MGI:5758867	Mouse	PMID:28973536
Biological Process	GO:0006878	intracellular copper ion homeostasis	Sco1	IMP	MGI:MGI:2386742,MGI:MGI:5758867	Mouse	PMID:28973536
Biological Process	GO:0006878	intracellular copper ion homeostasis	Sco1	IDA		Mouse	PMID:28647369
Biological Process	GO:0006878	intracellular copper ion homeostasis	Sco1	IMP	MGI:MGI:2176228,MGI:MGI:5758867	Mouse	PMID:25683716
Biological Process	GO:0006878	intracellular copper ion homeostasis	Sco1	IMP	MGI:MGI:2182095,MGI:MGI:5758867	Mouse	PMID:28973536
Biological Process	GO:0033617	mitochondrial cytochrome c oxidase assembly	SCO1	IMP		Human	PMID:15229189
Biological Process	GO:0033617	mitochondrial cytochrome c oxidase assembly	Sco1	IMP	MGI:MGI:2176228,MGI:MGI:5758867	Mouse	PMID:25683716
Biological Process	GO:1900077	negative regulation of cellular response to insulin stimulus	Sco1	IDA		Mouse	PMID:28973536
Biological Process	GO:1901799	negative regulation of proteasomal protein catabolic process	Sco1	IMP	MGI:MGI:2176228,MGI:MGI:5758867	Mouse	PMID:25683716
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	Sco1	IDA		Mouse	PMID:28647369
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	Sco1	IDA		Mouse	PMID:28973536
Biological Process	GO:0010498	proteasomal protein catabolic process	Sco1	IMP	MGI:MGI:2176228,MGI:MGI:5758867	Mouse	PMID:25683716
Biological Process	GO:0072659	protein localization to plasma membrane	Sco1	IMP	MGI:MGI:2386742,MGI:MGI:5758867	Mouse	PMID:28973536
Biological Process	GO:1904959	regulation of cytochrome-c oxidase activity	Sco1	IMP	MGI:MGI:2386742,MGI:MGI:5758867	Mouse	PMID:28973536
Biological Process	GO:1904959	regulation of cytochrome-c oxidase activity	Sco1	IMP	MGI:MGI:2182095,MGI:MGI:5758867	Mouse	PMID:28973536

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern