Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCIN
  • Mouse genes Scin
  • Rat genes Scin
  • Zfish genes scin
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scin

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005903	brush border	Scin	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0070062	extracellular exosome	SCIN	HDA		Human	PMID:19056867
Cellular Component	GO:0032991	protein-containing complex	Scin	IDA		Rat	PMID:15823548|RGD:1600561
Biological Process	GO:0051693	actin filament capping	SCIN	IMP		Human	PMID:19666531
Biological Process	GO:0051014	actin filament severing	SCIN	IMP		Human	PMID:11568009
Biological Process	GO:0008285	negative regulation of cell population proliferation	SCIN	IMP		Human	PMID:11568009
Biological Process	GO:0051127	positive regulation of actin nucleation	SCIN	IMP		Human	PMID:19666531
Biological Process	GO:0043065	positive regulation of apoptotic process	SCIN	IMP		Human	PMID:11568009
Biological Process	GO:0045654	positive regulation of megakaryocyte differentiation	SCIN	IMP		Human	PMID:11568009
Biological Process	GO:0042989	sequestering of actin monomers	SCIN	IMP		Human	PMID:19666531

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern