Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SASH1
  • Mouse genes Sash1
  • Rat genes Sash1
  • Zfish genes sash1a,sash1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sash1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	SASH1	IDA		Human	PMID:23333244
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	SASH1	IDA		Human	PMID:23776175
Molecular Function	GO:0060090	molecular adaptor activity	SASH1	IDA		Human	PMID:23776175
Molecular Function	GO:0005515	protein binding	SASH1	IPI	UniProtKB:P46940	Human	PMID:23333244
Molecular Function	GO:0005515	protein binding	SASH1	IDA		Human	PMID:23776175
Molecular Function	GO:0019901	protein kinase binding	SASH1	IDA		Human	PMID:23776175
Cellular Component	GO:0005737	cytoplasm	SASH1	IDA		Human	PMID:23333244
Cellular Component	GO:0016020	membrane	Sash1	IDA		Mouse	PMID:23776175
Cellular Component	GO:0032991	protein-containing complex	SASH1	IMP		Human	PMID:23776175
Biological Process	GO:0045766	positive regulation of angiogenesis	SASH1	IMP		Human	PMID:23776175
Biological Process	GO:0010595	positive regulation of endothelial cell migration	SASH1	IDA		Human	PMID:23776175
Biological Process	GO:0043507	positive regulation of JUN kinase activity	SASH1	IMP		Human	PMID:23776175
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	SASH1	IMP		Human	PMID:23776175
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	SASH1	IMP		Human	PMID:23776175
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	SASH1	IMP		Human	PMID:23776175
Biological Process	GO:0000209	protein polyubiquitination	SASH1	IDA		Human	PMID:23776175
Biological Process	GO:0010632	regulation of epithelial cell migration	SASH1	IMP		Human	PMID:23333244
Biological Process	GO:1902498	regulation of protein autoubiquitination	SASH1	IDA		Human	PMID:23776175
Biological Process	GO:1900044	regulation of protein K63-linked ubiquitination	SASH1	IDA		Human	PMID:23776175

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern