Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SACS
  • Mouse genes Sacs
  • Rat genes Sacs
  • Zfish genes sacs
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sacs

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030544	Hsp70 protein binding	SACS	IPI	UniProtKB:A1A766	Human	PMID:19208651
Molecular Function	GO:0042802	identical protein binding	SACS	IPI	UniProtKB:Q9NZJ4	Human	PMID:21507954
Molecular Function	GO:0070628	proteasome binding	SACS	IPI	UniProtKB:P25788	Human	PMID:19208651
Molecular Function	GO:0051087	protein-folding chaperone binding	SACS	IDA		Human	PMID:19208651
Cellular Component	GO:0005737	cytoplasm	SACS	IDA		Human	PMID:19208651
Cellular Component	GO:0005739	mitochondrion	SACS	IDA		Human	PMID:19208651
Cellular Component	GO:0005634	nucleus	SACS	IDA		Human	PMID:19208651
Biological Process	GO:0090084	negative regulation of inclusion body assembly	SACS	IMP		Human	PMID:19208651

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern