Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RXFP2
  • Mouse genes Rxfp2
  • Rat genes Rxfp2
  • Zfish genes rxfp2a,rxfp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rxfp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017046	peptide hormone binding	Rxfp2	IPI	RGD:736797	Rat	PMID:15956681|RGD:1600172
Molecular Function	GO:0016500	protein-hormone receptor activity	Rxfp2	IMP	MGI:MGI:2388129	Mouse	PMID:12217959
Cellular Component	GO:0005886	plasma membrane	Rxfp2	IDA		Rat	PMID:11732985|RGD:1600185
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Rxfp2	IMP	MGI:MGI:2388129	Mouse	PMID:12217959
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Rxfp2	IDA		Rat	PMID:15123806|RGD:1600181
Biological Process	GO:0008584	male gonad development	Rxfp2	IMP	MGI:MGI:2388129	Mouse	PMID:12217959
Biological Process	GO:0043066	negative regulation of apoptotic process	Rxfp2	IDA		Rat	PMID:15123806|RGD:1600181
Biological Process	GO:0008285	negative regulation of cell population proliferation	Rxfp2	IDA		Rat	PMID:15956754|RGD:1600165
Biological Process	GO:0001556	oocyte maturation	Rxfp2	IDA		Rat	PMID:15123806|RGD:1600181
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Rxfp2	IDA		Rat	PMID:15956681|RGD:1600172

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern