Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RTN4RL2
  • Mouse genes Rtn4rl2
  • Rat genes Rtn4rl2
  • Zfish genes rtn4rl2a,rtn4rl2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rtn4rl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Rtn4rl2	IPI	UniProtKB:P07722	Rat	PMID:15673660|RGD:12790657
Molecular Function	GO:0005515	protein binding	Rtn4rl2	IPI	UniProtKB:P07722	Rat	PMID:19420245|RGD:12050099
Molecular Function	GO:0005515	protein binding	rtn4rl2b	IPI	ZFIN:ZDB-GENE-030710-1	Zfish	PMID:24466042
Molecular Function	GO:0005515	protein binding	rtn4rl2a	IPI	ZFIN:ZDB-GENE-030710-1	Zfish	PMID:24466042
Molecular Function	GO:0038023	signaling receptor activity	RTN4RL2	IDA		Human	PMID:12694398
Molecular Function	GO:0038023	signaling receptor activity	Rtn4rl2	IMP		Rat	PMID:15673660|RGD:12790657
Cellular Component	GO:0030424	axon	Rtn4rl2	IDA		Rat	PMID:15673660|RGD:12790657
Cellular Component	GO:0009986	cell surface	RTN4RL2	IDA		Human	PMID:20463223
Cellular Component	GO:0009986	cell surface	Rtn4rl2	IDA		Rat	PMID:15673660|RGD:12790657
Cellular Component	GO:0009897	external side of plasma membrane	Rtn4rl2	IDA		Rat	PMID:12694398|RGD:1299553
Cellular Component	GO:0070062	extracellular exosome	RTN4RL2	HDA		Human	PMID:23533145
Cellular Component	GO:0045121	membrane raft	Rtn4rl2	IDA		Rat	PMID:12694398|RGD:1299553
Cellular Component	GO:0045121	membrane raft	Rtn4rl2	IDA		Rat	PMID:15673660|RGD:12790657
Cellular Component	GO:0043005	neuron projection	Rtn4rl2	IDA		Rat	PMID:15673660|RGD:12790657
Cellular Component	GO:0043204	perikaryon	Rtn4rl2	IDA		Rat	PMID:15673660|RGD:12790657
Cellular Component	GO:0005886	plasma membrane	RTN4RL2	IDA		Human	PMID:12694398
Biological Process	GO:0007166	cell surface receptor signaling pathway	Rtn4rl2	IMP		Rat	PMID:15673660|RGD:12790657
Biological Process	GO:0022038	corpus callosum development	Rtn4rl2	IMP		Mouse	MGI:MGI:5824191|PMID:27339102
Biological Process	GO:0010977	negative regulation of neuron projection development	Rtn4rl2	IMP		Mouse	MGI:MGI:5461303|PMID:22406547
Biological Process	GO:0010977	negative regulation of neuron projection development	Rtn4rl2	IMP		Rat	PMID:15673660|RGD:12790657
Biological Process	GO:0048916	posterior lateral line development	rtn4rl2a	IGI	ZFIN:ZDB-MRPHLNO-140521-2,ZFIN:ZDB-MRPHLNO-140521-4	Zfish	PMID:24466042
Biological Process	GO:0048922	posterior lateral line neuromast deposition	rtn4rl2a	IGI	ZFIN:ZDB-MRPHLNO-140521-2,ZFIN:ZDB-MRPHLNO-140521-4	Zfish	PMID:24466042

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern