Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RTN2
  • Mouse genes Rtn2
  • Rat genes Rtn2
  • Zfish genes rtn2a,rtn2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rtn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RTN2	IPI	UniProtKB:P56817	Human	PMID:15286784
Molecular Function	GO:0005515	protein binding	RTN2	IPI	UniProtKB:Q9UBP0-1	Human	PMID:22232211
Molecular Function	GO:0005515	protein binding	Rtn2	IPI	UniProtKB:P51907	Rat	PMID:18096700|RGD:40902968
Molecular Function	GO:0005515	protein binding	Rtn2	IPI	UniProtKB:Q9ES40	Rat	PMID:18096700|RGD:40902968
Cellular Component	GO:0009986	cell surface	Rtn2	IDA		Rat	PMID:18096700|RGD:40902968
Cellular Component	GO:0005783	endoplasmic reticulum	RTN2	IDA		Human	PMID:22232211
Cellular Component	GO:0005783	endoplasmic reticulum	Rtn2	IDA		Rat	PMID:18096700|RGD:40902968
Cellular Component	GO:0005882	intermediate filament	Rtn2	IDA		Mouse	MGI:MGI:6478978|PMID:10672514
Cellular Component	GO:0030315	T-tubule	Rtn2	IDA		Mouse	PMID:19720795
Cellular Component	GO:0014802	terminal cisterna	Rtn2	IDA		Mouse	PMID:19720795
Cellular Component	GO:0030018	Z disc	Rtn2	IDA		Mouse	MGI:MGI:6478978|PMID:10672514
Biological Process	GO:0010467	gene expression	Rtn2	IPI	UniProtKB:Q6WN19	Mouse	PMID:18096700
Biological Process	GO:0065002	intracellular protein transmembrane transport	Rtn2	IMP	MGI:MGI:3528884	Mouse	PMID:19720795
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	RTN2	IDA		Human	PMID:15286784
Biological Process	GO:0015031	protein transport	Rtn2	IDA		Rat	PMID:18096700|RGD:40902968
Biological Process	GO:0046324	regulation of glucose import	Rtn2	IMP	MGI:MGI:3528884	Mouse	PMID:19720795

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern