Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RTCB
  • Mouse genes Rtcb
  • Rat genes Rtcb
  • Zfish genes rtcb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rtcb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RTCB	IPI	UniProtKB:Q9Y224	Human	PMID:24608264
Molecular Function	GO:0005515	protein binding	RTCB	IPI	UniProtKB:Q8IWT0	Human	PMID:24870230
Molecular Function	GO:0005515	protein binding	RTCB	IPI	UniProtKB:Q9UKG1	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	RTCB	IPI	UniProtKB:Q9Y224	Human	PMID:30833792
Molecular Function	GO:0003723	RNA binding	RTCB	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	RTCB	HDA		Human	PMID:22681889
Molecular Function	GO:0003972	RNA ligase (ATP) activity	RTCB	IDA		Human	PMID:21311021
Molecular Function	GO:0003972	RNA ligase (ATP) activity	RTCB	IMP		Human	PMID:24870230
Molecular Function	GO:0017166	vinculin binding	RTCB	IPI	UniProtKB:P18206	Human	PMID:15163412
Cellular Component	GO:0005737	cytoplasm	RTCB	IDA		Human	PMID:24608264
Cellular Component	GO:0005737	cytoplasm	Rtcb	IDA		Mouse	PMID:20510672
Cellular Component	GO:0005829	cytosol	RTCB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Rtcb	IDA		Mouse	MGI:MGI:5606218|PMID:25087875
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RTCB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005635	nuclear envelope	Rtcb	IDA		Mouse	MGI:MGI:5606218|PMID:25087875
Cellular Component	GO:0005654	nucleoplasm	RTCB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RTCB	IDA		Human	PMID:24608264
Cellular Component	GO:0072669	tRNA-splicing ligase complex	RTCB	IDA		Human	PMID:21311021
Cellular Component	GO:0072669	tRNA-splicing ligase complex	RTCB	IDA		Human	PMID:24870230
Biological Process	GO:0001701	in utero embryonic development	Rtcb	IMP		Mouse	PMID:20510672
Biological Process	GO:0001890	placenta development	Rtcb	IMP		Mouse	PMID:20510672
Biological Process	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	RTCB	IDA		Human	PMID:21311021
Biological Process	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	RTCB	IDA		Human	PMID:24870230

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern