Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RSAD2
  • Mouse genes Rsad2
  • Rat genes Rsad2
  • Zfish genes rsad2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rsad2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	RSAD2	IDA		Human	PMID:20176015
Molecular Function	GO:0005515	protein binding	RSAD2	IPI	UniProtKB:P16778	Human	PMID:21527675
Molecular Function	GO:0005515	protein binding	RSAD2	IPI	UniProtKB:P55084	Human	PMID:21527675
Molecular Function	GO:0005515	protein binding	RSAD2	IPI	UniProtKB:Q9P0L0	Human	PMID:21957124
Molecular Function	GO:0005515	protein binding	RSAD2	IPI	UniProtKB:Q9P0L0	Human	PMID:22045669
Molecular Function	GO:0005515	protein binding	RSAD2	IPI	UniProtKB:O76071	Human	PMID:24245804
Molecular Function	GO:0005515	protein binding	RSAD2	IPI	UniProtKB:P02654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSAD2	IPI	UniProtKB:P55056	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSAD2	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rsad2	IPI	UniProtKB:P55084	Mouse	MGI:MGI:5427072|PMID:21527675
Molecular Function	GO:0005515	protein binding	Rsad2	IPI	UniProtKB:P70196|UniProtKB:Q62406	Mouse	MGI:MGI:4943343|PMID:21435586
Molecular Function	GO:0043621	protein self-association	RSAD2	IDA		Human	PMID:19074433
Cellular Component	GO:0005783	endoplasmic reticulum	RSAD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	RSAD2	IDA		Human	PMID:11752458
Cellular Component	GO:0005783	endoplasmic reticulum	RSAD2	IDA		Human	PMID:21527675
Cellular Component	GO:0005783	endoplasmic reticulum	Rsad2	IDA		Mouse	MGI:MGI:5469996|PMID:23160199
Cellular Component	GO:0005789	endoplasmic reticulum membrane	RSAD2	IDA		Human	PMID:19074433
Cellular Component	GO:0001650	fibrillar center	RSAD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005811	lipid droplet	Rsad2	IDA		Mouse	MGI:MGI:4943343|PMID:21435586
Cellular Component	GO:0005811	lipid droplet	Rsad2	IDA		Mouse	MGI:MGI:5430879|PMID:19920176
Cellular Component	GO:0005743	mitochondrial inner membrane	RSAD2	IDA		Human	PMID:21527675
Cellular Component	GO:0005741	mitochondrial outer membrane	RSAD2	IDA		Human	PMID:21527675
Cellular Component	GO:0005739	mitochondrion	RSAD2	IDA		Human	PMID:21527675
Biological Process	GO:0035710	CD4-positive, alpha-beta T cell activation	Rsad2	IMP		Mouse	MGI:MGI:3844206|PMID:19047684
Biological Process	GO:0043367	CD4-positive, alpha-beta T cell differentiation	Rsad2	IMP		Mouse	MGI:MGI:3844206|PMID:19047684
Biological Process	GO:0051607	defense response to virus	RSAD2	IDA		Human	PMID:16108059
Biological Process	GO:0051607	defense response to virus	RSAD2	IDA		Human	PMID:16982913
Biological Process	GO:0051607	defense response to virus	RSAD2	IDA		Human	PMID:9391139
Biological Process	GO:0051607	defense response to virus	Rsad2	IDA		Mouse	MGI:MGI:3765256|PMID:17686841
Biological Process	GO:0050709	negative regulation of protein secretion	RSAD2	IDA		Human	PMID:19074433
Biological Process	GO:0045071	negative regulation of viral genome replication	RSAD2	IDA		Human	PMID:21957124
Biological Process	GO:0045071	negative regulation of viral genome replication	Rsad2	IMP		Mouse	MGI:MGI:5431072|PMID:21880757
Biological Process	GO:0001503	ossification	Rsad2	IDA		Rat	PMID:10698968|RGD:631877
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	Rsad2	IMP		Mouse	MGI:MGI:3844206|PMID:19047684
Biological Process	GO:0034157	positive regulation of toll-like receptor 7 signaling pathway	Rsad2	IMP		Mouse	MGI:MGI:4943343|PMID:21435586
Biological Process	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway	Rsad2	IMP		Mouse	MGI:MGI:4943343|PMID:21435586
Biological Process	GO:0030278	regulation of ossification	Rsad2	IDA		Rat	PMID:10698968|RGD:631877
Biological Process	GO:0009615	response to virus	RSAD2	IDA		Human	PMID:21957124
Biological Process	GO:0009615	response to virus	Rsad2	IMP		Mouse	MGI:MGI:5431072|PMID:21880757
Biological Process	GO:0009615	response to virus	rsad2	IDA		Zfish	PMID:17371995

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern