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Rsad2
Gene Detail
Symbol

Name
ID
Rsad2
radical S-adenosyl methionine domain containing 2
MGI:1929628
Synonyms
2510004L01Rik, cig5, Vig1, viperin
Feature Type
protein coding gene
Genetic Map
Chromosome 12
9.69 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:26442753-26456452 bp, - strand
From VEGA annotation of GRCm38

  13700 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10969  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RSAD2
Gene Tree: Rsad2

Human
homologs
RSAD2, radical S-adenosyl methionine domain containing 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 91543
neXtProt AC: NX_Q8WXG1

Human Synonyms: 2510004L01Rik, cig33, cig5, vig1

Human Chr (Location): 2p25.2; chr2:6865840-6898232 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit impaired T-helper 2 differentitation.
 
Interactions
Rsad2 interacts with 352 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(85)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rsad2 ; ZFIN rsad2    NEW 
Molecular
reagents
All nucleic(85) cDNA(85)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000027569 (Evidence)
Ensembl Gene Model ENSMUSG00000020641 (Evidence)
Entrez Gene 58185 (Evidence)
DFCI TC1644965, TC1573798, TC1692484
DoTS DT.110926428, DT.110926396, DT.99866452, DT.487691, DT.101406617, DT.101406615, DT.101130489
NIA Mouse Gene Index U033851
Consensus CDS Project CCDS25848.1
International Mouse Phenotyping Consortium Status Rsad2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027569 VEGA Gene Model | MGI Sequence Detail 13700 C57BL/6J ±  kb
transcript OTTMUST00000068265 VEGA | MGI Sequence Detail 3775 Not Applicable 
polypeptide OTTMUSP00000034468 VEGA | MGI Sequence Detail 362 Not Applicable 

For the selected sequences
All sequences(121) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(275 from dbSNP Build 137)    SNPs within 2kb including multiple locations(279)
Protein-related
information
ResourceIDDescription
InterPro IPR013785 Aldolase-type TIM barrel
InterPro IPR026372 Antiviral radical SAM protein viperin
InterPro IPR006638 Elongator protein 3/MiaB/NifB
InterPro IPR007197 Radical SAM
Protein Ontology PR:000014318 radical S-adenosyl methionine domain-containing protein 2
References
(Earliest) J:66317 Boudinot P, et al., vig-1, a new fish gene induced by the rhabdovirus glycoprotein, has a virus-induced homologue in humans and shares conserved motifs with the MoaA family. J Virol. 1999 Mar;73(3):1846-52
(Latest) J:193971 Teng TS, et al., Viperin restricts chikungunya virus replication and pathology. J Clin Invest. 2012 Dec 3;122(12):4447-60
All references(40)
Other
accession IDs
MGI:1919695

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory