Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RRAGC
  • Mouse genes Rragc
  • Rat genes Rragc
  • Zfish genes rragca,rragcb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rragc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RRAGC	IDA		Human	PMID:11073942
Molecular Function	GO:0019003	GDP binding	RRAGC	IMP		Human	PMID:22424946
Molecular Function	GO:0005525	GTP binding	RRAGC	IDA		Human	PMID:11073942
Molecular Function	GO:0005525	GTP binding	RRAGC	IMP		Human	PMID:22424946
Molecular Function	GO:0005525	GTP binding	RRAGC	IMP		Human	PMID:23723238
Molecular Function	GO:0003924	GTPase activity	RRAGC	IDA		Human	PMID:11073942
Molecular Function	GO:0003924	GTPase activity	RRAGC	IDA		Human	PMID:23723238
Molecular Function	GO:0051020	GTPase binding	RRAGC	IPI	UniProtKB:Q5VZM2	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q5VZM2	Human	PMID:11073942
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q7L523	Human	PMID:11073942
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q76FK4	Human	PMID:14660641
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q7L523	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q5VZM2	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q7L523	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q5VZM2	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q5VZM2,UniProtKB:Q6IAA8	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q7L523	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q9P0V3	Human	PMID:22575674
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:P58006	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:P58043	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q9CYP7	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q5VZM2	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q7L523	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q8NBW4	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q5VZM2	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q7L523	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q8NBW4	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:O15118,UniProtKB:Q6IAA8,UniProtKB:Q7L523,UniProtKB:Q8NBW4	Human	PMID:28336668
Molecular Function	GO:0005515	protein binding	RRAGC	IPI	UniProtKB:Q7L523	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Rragc	IPI	UniProtKB:Q3TWL2	Mouse	MGI:MGI:6304515|PMID:29644770
Molecular Function	GO:0046982	protein heterodimerization activity	RRAGC	IPI	UniProtKB:Q7L523	Human	PMID:11073942
Cellular Component	GO:0005737	cytoplasm	RRAGC	IDA		Human	PMID:11073942
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RRAGC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	RRAGC	IDA		Human	PMID:20381137
Cellular Component	GO:0005654	nucleoplasm	RRAGC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RRAGC	IDA		Human	PMID:11073942
Biological Process	GO:0034198	cellular response to amino acid starvation	RRAGC	IGI	UniProtKB:Q5VZM2	Human	PMID:23723238
Biological Process	GO:0032006	regulation of TOR signaling	RRAGC	IGI	UniProtKB:Q5VZM2	Human	PMID:23723238
Biological Process	GO:1903432	regulation of TORC1 signaling	RRAGC	IMP		Human	PMID:27222292
Biological Process	GO:0043200	response to amino acid	RRAGC	IMP		Human	PMID:27222292

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern