Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RRAGB
  • Mouse genes Rragb
  • Rat genes RragB
  • Zfish genes rraga
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rragb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005525	GTP binding	RRAGB	IMP		Human	PMID:22424946
Molecular Function	GO:0005525	GTP binding	RRAGB	IMP		Human	PMID:23723238
Molecular Function	GO:0005525	GTP binding	RRAGB	IDA		Human	PMID:7499430
Molecular Function	GO:0005525	GTP binding	RragB	IDA		Rat	PMID:7499430|RGD:633888
Molecular Function	GO:0003924	GTPase activity	RRAGB	IDA		Human	PMID:23723238
Molecular Function	GO:0051020	GTPase binding	RRAGB	IPI	UniProtKB:Q9HB90	Human	PMID:22424946
Molecular Function	GO:0051020	GTPase binding	RRAGB	IPI	UniProtKB:Q9NQL2	Human	PMID:22424946
Molecular Function	GO:0032561	guanyl ribonucleotide binding	RRAGB	IDA		Human	PMID:22575674
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9HB90	Human	PMID:11073942
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9NQL2	Human	PMID:11073942
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q6IAA8	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9HB90	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9NQL2	Human	PMID:20381137
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q6IAA8,UniProtKB:Q9HB90	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q6IAA8,UniProtKB:Q9NQL2	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9HB90	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9NQL2	Human	PMID:22424946
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9P0V3	Human	PMID:22575674
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:P11279	Human	PMID:23394946
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:P58006	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:P58043	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9CYP7	Human	PMID:25259925
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q8NBW4	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9HB90	Human	PMID:25561175
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q8NBW4	Human	PMID:25567906
Molecular Function	GO:0005515	protein binding	RRAGB	IPI	UniProtKB:Q9HB90	Human	PMID:25567906
Cellular Component	GO:0005737	cytoplasm	RRAGB	IDA		Human	PMID:9394008
Cellular Component	GO:0005765	lysosomal membrane	RRAGB	HDA		Human	PMID:17897319
Cellular Component	GO:0005764	lysosome	RRAGB	IDA		Human	PMID:20381137
Biological Process	GO:0034198	cellular response to amino acid starvation	RRAGB	IGI	UniProtKB:Q9HB90	Human	PMID:23723238
Biological Process	GO:0071230	cellular response to amino acid stimulus	RRAGB	IMP		Human	PMID:20381137
Biological Process	GO:1990253	cellular response to leucine starvation	RRAGB	IMP		Human	PMID:22424946
Biological Process	GO:0022010	central nervous system myelination	rraga	IGI	ZFIN:ZDB-GENO-190307-19	Zfish	PMID:30399334
Biological Process	GO:0032008	positive regulation of TOR signaling	RRAGB	IMP		Human	PMID:22575674
Biological Process	GO:1904263	positive regulation of TORC1 signaling	RRAGB	IMP		Human	PMID:22424946
Biological Process	GO:0008104	protein localization	RRAGB	IMP		Human	PMID:20381137
Biological Process	GO:2000425	regulation of apoptotic cell clearance	rraga	IMP	ZFIN:ZDB-GENO-170206-2	Zfish	PMID:26774477
Biological Process	GO:1905671	regulation of lysosome organization	rraga	IMP	ZFIN:ZDB-GENO-170206-2	Zfish	PMID:26774477
Biological Process	GO:0032006	regulation of TOR signaling	RRAGB	IGI	UniProtKB:Q9HB90	Human	PMID:23723238

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern