Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ROMO1
  • Mouse genes Romo1
  • Rat genes Romo1
  • Zfish genes romo1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Romo1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ROMO1	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ROMO1	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Cellular Component	GO:0005739	mitochondrion	ROMO1	IDA		Human	PMID:16842742
Cellular Component	GO:0005739	mitochondrion	Romo1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Romo1	HDA		Mouse	PMID:18614015
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ROMO1	IMP		Human	PMID:22083756
Biological Process	GO:0034614	cellular response to reactive oxygen species	ROMO1	IMP		Human	PMID:18836179
Biological Process	GO:0051838	cytolysis by host of symbiont cells	ROMO1	IDA		Human	PMID:22083756
Biological Process	GO:0042742	defense response to bacterium	ROMO1	IDA		Human	PMID:22083756
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ROMO1	IDA		Human	PMID:22083756
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ROMO1	IMP		Human	PMID:22083756
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ROMO1	IDA		Human	PMID:22083756
Biological Process	GO:0031640	killing of cells of another organism	ROMO1	IDA		Human	PMID:22083756
Biological Process	GO:0031640	killing of cells of another organism	ROMO1	IMP		Human	PMID:22083756
Biological Process	GO:0008284	positive regulation of cell population proliferation	ROMO1	IDA		Human	PMID:18313394
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	ROMO1	IDA		Human	PMID:16842742
Biological Process	GO:0090399	replicative senescence	ROMO1	IMP		Human	PMID:18836179

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern