Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF185
  • Mouse genes Rnf185
  • Rat genes Rnf185
  • Zfish genes rnf185
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf185

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008047	enzyme activator activity	RNF185	IDA		Human	PMID:28273161
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:P51668	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:P62837	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q969T4	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q96LR5	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q9Y2X8	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q12981	Human	PMID:21931693
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:O94905	Human	PMID:24019521
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:O75915	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q969T4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q96DZ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q99942	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q9BSR8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q9BWQ6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:P55061	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q969T4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:A6NDP7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:P51668	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:P61086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:P62837	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q0D2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q8N2M4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q8NBI2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q969T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q96D05-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q96HH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q96LR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q9BVK8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q9BWQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF185	IPI	UniProtKB:Q9Y2X8	Human	PMID:32296183
Molecular Function	GO:0044877	protein-containing complex binding	RNF185	IPI	UniProtKB:Q9BUN8	Human	PMID:24019521
Molecular Function	GO:0043130	ubiquitin binding	RNF185	IDA		Human	PMID:27485036
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF185	IDA		Human	PMID:24019521
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF185	IDA		Human	PMID:27485036
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF185	IDA		Human	PMID:28273161
Molecular Function	GO:0044390	ubiquitin-like protein conjugating enzyme binding	RNF185	IPI	UniProtKB:Q8N2K1	Human	PMID:24019521
Molecular Function	GO:0044390	ubiquitin-like protein conjugating enzyme binding	RNF185	IPI	UniProtKB:Q9Y385	Human	PMID:24019521
Cellular Component	GO:0005783	endoplasmic reticulum	RNF185	IDA		Human	PMID:24019521
Cellular Component	GO:0005783	endoplasmic reticulum	RNF185	IDA		Human	PMID:27485036
Biological Process	GO:0051607	defense response to virus	RNF185	IDA		Human	PMID:28273161
Biological Process	GO:0036503	ERAD pathway	RNF185	IGI	UniProtKB:Q99942	Human	PMID:24019521
Biological Process	GO:1904294	positive regulation of ERAD pathway	RNF185	IMP		Human	PMID:27485036
Biological Process	GO:0045089	positive regulation of innate immune response	RNF185	IDA		Human	PMID:28273161
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	RNF185	IDA		Human	PMID:28273161
Biological Process	GO:0051865	protein autoubiquitination	RNF185	IDA		Human	PMID:24019521
Biological Process	GO:0051865	protein autoubiquitination	RNF185	IDA		Human	PMID:27485036
Biological Process	GO:0044314	protein K27-linked ubiquitination	RNF185	IDA		Human	PMID:28273161
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	RNF185	IMP		Human	PMID:24019521

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern