Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF180
  • Mouse genes Rnf180
  • Rat genes Rnf180
  • Zfish genes rnf180a,rnf180b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf180

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Rnf180	IPI	PR:Q62520	Mouse	PMID:18363970
Molecular Function	GO:0005515	protein binding	Rnf180	IPI	PR:Q64133	Mouse	PMID:23926250
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	Rnf180	IDA		Mouse	PMID:18363970
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Rnf180	IDA		Mouse	PMID:18363970
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Rnf180	IDA		Mouse	PMID:18363970
Biological Process	GO:0030534	adult behavior	Rnf180	IMP		Mouse	PMID:23926250
Biological Process	GO:0042415	norepinephrine metabolic process	Rnf180	IMP		Mouse	PMID:23926250
Biological Process	GO:1901360	organic cyclic compound metabolic process	Rnf180	IMP		Mouse	PMID:23926250
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Rnf180	IDA		Mouse	PMID:18363970
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Rnf180	IDA		Mouse	PMID:23926250
Biological Process	GO:0031398	positive regulation of protein ubiquitination	Rnf180	IDA		Mouse	PMID:23926250
Biological Process	GO:0000209	protein polyubiquitination	Rnf180	IDA		Mouse	PMID:23926250
Biological Process	GO:0050790	regulation of catalytic activity	Rnf180	IMP		Mouse	PMID:23926250
Biological Process	GO:0042428	serotonin metabolic process	Rnf180	IMP		Mouse	PMID:23926250

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern