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Gene Ontology Browser
Term Detail
GO term:serotonin metabolic process
Synonym: serotonin metabolism
GO id:GO:0042428
Definition:The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Number of paths to term: 16

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular aromatic compound metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular aromatic compound metabolic process
                                        is-aphenol-containing compound metabolic process
                                                is-a(+)-lariciresinol metabolic process +
                                                is-a(+)-larreatricin metabolic process
                                                is-a(+)-pinoresinol metabolic process +
                                                is-a(-)-lariciresinol metabolic process +
                                                is-a(-)-pinoresinol metabolic process +
                                                is-a(R)-4-hydroxymandelate metabolic process +
                                                is-a1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process +
                                                is-a3-hydroxybenzyl alcohol metabolic process
                                                is-a3-hydroxyphenylacetate metabolic process +
                                                is-a4-hydroxyphenylacetate metabolic process +
                                                is-a4-nitrophenol metabolic process +
                                                is-aaerobic phenol-containing compound metabolic process +
                                                is-aanaerobic phenol-containing compound metabolic process +
                                                is-aansamycin metabolic process +
                                                is-abromoxynil metabolic process
                                                is-acatechol-containing compound metabolic process +
                                                is-acresol metabolic process +
                                                is-acurcumin metabolic process +
                                                is-adiorcinol metabolic process +
                                                is-aemericellin metabolic process +
                                                is-aendocrocin metabolic process +
                                                is-aF-9775A metabolic process +
                                                is-aF-9775B metabolic process +
                                                is-aferulate metabolic process +
                                                is-afunalenone metabolic process +
                                                is-agallate metabolic process +
                                                is-ahomogentisate metabolic process +
                                                is-amelanin metabolic process +
                                                is-amonodictyphenone metabolic process +
                                                is-aneosartoricin metabolic process +
                                                is-ao-orsellinic acid metabolic process +
                                                is-aoctopamine metabolic process +
                                                is-aorcinol metabolic process +
                                                is-aoxytetracycline metabolic process +
                                                is-apentachlorophenol metabolic process +
                                                is-aphenol metabolic process +
                                                is-aphenol-containing compound biosynthetic process +
                                                is-aphenol-containing compound catabolic process +
                                                is-apyochelin metabolic process +
                                                is-aresorcinol metabolic process
                                                is-asalicylic acid metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process
                                                is-ashamixanthone metabolic process +
                                                is-asinapate ester metabolic process +
                                                is-asinapate metabolic process +
                                                is-atetracycline metabolic process +
                                                is-athyroid hormone metabolic process +
                                                is-avanillin metabolic process +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular nitrogen compound metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aheterocycle metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular aromatic compound metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular aromatic compound metabolic process
                                        is-aphenol-containing compound metabolic process
                                                is-a(+)-lariciresinol metabolic process +
                                                is-a(+)-larreatricin metabolic process
                                                is-a(+)-pinoresinol metabolic process +
                                                is-a(-)-lariciresinol metabolic process +
                                                is-a(-)-pinoresinol metabolic process +
                                                is-a(R)-4-hydroxymandelate metabolic process +
                                                is-a1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process +
                                                is-a3-hydroxybenzyl alcohol metabolic process
                                                is-a3-hydroxyphenylacetate metabolic process +
                                                is-a4-hydroxyphenylacetate metabolic process +
                                                is-a4-nitrophenol metabolic process +
                                                is-aaerobic phenol-containing compound metabolic process +
                                                is-aanaerobic phenol-containing compound metabolic process +
                                                is-aansamycin metabolic process +
                                                is-abromoxynil metabolic process
                                                is-acatechol-containing compound metabolic process +
                                                is-acresol metabolic process +
                                                is-acurcumin metabolic process +
                                                is-adiorcinol metabolic process +
                                                is-aemericellin metabolic process +
                                                is-aendocrocin metabolic process +
                                                is-aF-9775A metabolic process +
                                                is-aF-9775B metabolic process +
                                                is-aferulate metabolic process +
                                                is-afunalenone metabolic process +
                                                is-agallate metabolic process +
                                                is-ahomogentisate metabolic process +
                                                is-amelanin metabolic process +
                                                is-amonodictyphenone metabolic process +
                                                is-aneosartoricin metabolic process +
                                                is-ao-orsellinic acid metabolic process +
                                                is-aoctopamine metabolic process +
                                                is-aorcinol metabolic process +
                                                is-aoxytetracycline metabolic process +
                                                is-apentachlorophenol metabolic process +
                                                is-aphenol metabolic process +
                                                is-aphenol-containing compound biosynthetic process +
                                                is-aphenol-containing compound catabolic process +
                                                is-apyochelin metabolic process +
                                                is-aresorcinol metabolic process
                                                is-asalicylic acid metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process
                                                is-ashamixanthone metabolic process +
                                                is-asinapate ester metabolic process +
                                                is-asinapate metabolic process +
                                                is-atetracycline metabolic process +
                                                is-athyroid hormone metabolic process +
                                                is-avanillin metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular nitrogen compound metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aheterocycle metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-anitrogen compound metabolic process
                                is-acellular nitrogen compound metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-anitrogen compound metabolic process
                                is-aorganonitrogen compound metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-anitrogen compound metabolic process
                                is-aorganonitrogen compound metabolic process
                                        is-aprimary amino compound metabolic process
                                                is-a2-aminoethylphosphonate metabolic process +
                                                is-aatrazine catabolic process to isopropylamine
                                                is-aethanolamine metabolic process +
                                                is-amethylamine metabolic process +
                                                is-aphenylethylamine metabolic process +
                                                is-aphosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine
                                                is-aphosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline
                                                is-aphosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine
                                                is-aprimary amino compound biosynthetic process +
                                                is-aprimary amino compound catabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic cyclic compound metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic cyclic compound metabolic process
                                        is-aphenol-containing compound metabolic process
                                                is-a(+)-lariciresinol metabolic process +
                                                is-a(+)-larreatricin metabolic process
                                                is-a(+)-pinoresinol metabolic process +
                                                is-a(-)-lariciresinol metabolic process +
                                                is-a(-)-pinoresinol metabolic process +
                                                is-a(R)-4-hydroxymandelate metabolic process +
                                                is-a1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process +
                                                is-a3-hydroxybenzyl alcohol metabolic process
                                                is-a3-hydroxyphenylacetate metabolic process +
                                                is-a4-hydroxyphenylacetate metabolic process +
                                                is-a4-nitrophenol metabolic process +
                                                is-aaerobic phenol-containing compound metabolic process +
                                                is-aanaerobic phenol-containing compound metabolic process +
                                                is-aansamycin metabolic process +
                                                is-abromoxynil metabolic process
                                                is-acatechol-containing compound metabolic process +
                                                is-acresol metabolic process +
                                                is-acurcumin metabolic process +
                                                is-adiorcinol metabolic process +
                                                is-aemericellin metabolic process +
                                                is-aendocrocin metabolic process +
                                                is-aF-9775A metabolic process +
                                                is-aF-9775B metabolic process +
                                                is-aferulate metabolic process +
                                                is-afunalenone metabolic process +
                                                is-agallate metabolic process +
                                                is-ahomogentisate metabolic process +
                                                is-amelanin metabolic process +
                                                is-amonodictyphenone metabolic process +
                                                is-aneosartoricin metabolic process +
                                                is-ao-orsellinic acid metabolic process +
                                                is-aoctopamine metabolic process +
                                                is-aorcinol metabolic process +
                                                is-aoxytetracycline metabolic process +
                                                is-apentachlorophenol metabolic process +
                                                is-aphenol metabolic process +
                                                is-aphenol-containing compound biosynthetic process +
                                                is-aphenol-containing compound catabolic process +
                                                is-apyochelin metabolic process +
                                                is-aresorcinol metabolic process
                                                is-asalicylic acid metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process
                                                is-ashamixanthone metabolic process +
                                                is-asinapate ester metabolic process +
                                                is-asinapate metabolic process +
                                                is-atetracycline metabolic process +
                                                is-athyroid hormone metabolic process +
                                                is-avanillin metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic hydroxy compound metabolic process
                                        is-aphenol-containing compound metabolic process
                                                is-a(+)-lariciresinol metabolic process +
                                                is-a(+)-larreatricin metabolic process
                                                is-a(+)-pinoresinol metabolic process +
                                                is-a(-)-lariciresinol metabolic process +
                                                is-a(-)-pinoresinol metabolic process +
                                                is-a(R)-4-hydroxymandelate metabolic process +
                                                is-a1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process +
                                                is-a3-hydroxybenzyl alcohol metabolic process
                                                is-a3-hydroxyphenylacetate metabolic process +
                                                is-a4-hydroxyphenylacetate metabolic process +
                                                is-a4-nitrophenol metabolic process +
                                                is-aaerobic phenol-containing compound metabolic process +
                                                is-aanaerobic phenol-containing compound metabolic process +
                                                is-aansamycin metabolic process +
                                                is-abromoxynil metabolic process
                                                is-acatechol-containing compound metabolic process +
                                                is-acresol metabolic process +
                                                is-acurcumin metabolic process +
                                                is-adiorcinol metabolic process +
                                                is-aemericellin metabolic process +
                                                is-aendocrocin metabolic process +
                                                is-aF-9775A metabolic process +
                                                is-aF-9775B metabolic process +
                                                is-aferulate metabolic process +
                                                is-afunalenone metabolic process +
                                                is-agallate metabolic process +
                                                is-ahomogentisate metabolic process +
                                                is-amelanin metabolic process +
                                                is-amonodictyphenone metabolic process +
                                                is-aneosartoricin metabolic process +
                                                is-ao-orsellinic acid metabolic process +
                                                is-aoctopamine metabolic process +
                                                is-aorcinol metabolic process +
                                                is-aoxytetracycline metabolic process +
                                                is-apentachlorophenol metabolic process +
                                                is-aphenol metabolic process +
                                                is-aphenol-containing compound biosynthetic process +
                                                is-aphenol-containing compound catabolic process +
                                                is-apyochelin metabolic process +
                                                is-aresorcinol metabolic process
                                                is-asalicylic acid metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process
                                                is-ashamixanthone metabolic process +
                                                is-asinapate ester metabolic process +
                                                is-asinapate metabolic process +
                                                is-atetracycline metabolic process +
                                                is-athyroid hormone metabolic process +
                                                is-avanillin metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganonitrogen compound metabolic process
                                        is-aindole-containing compound metabolic process
                                                is-abrevianamide F metabolic process +
                                                is-afumiquinazoline F metabolic process +
                                                is-aindolalkylamine metabolic process +
                                                is-aindole glucosinolate metabolic process +
                                                is-aindole metabolic process +
                                                is-aindole phytoalexin metabolic process +
                                                is-aindole-containing compound biosynthetic process +
                                                is-aindole-containing compound catabolic process +
                                                is-aindoleacetic acid metabolic process +
                                                is-aindolebutyric acid metabolic process
                                                is-amelatonin metabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganonitrogen compound metabolic process
                                        is-aprimary amino compound metabolic process
                                                is-a2-aminoethylphosphonate metabolic process +
                                                is-aatrazine catabolic process to isopropylamine
                                                is-aethanolamine metabolic process +
                                                is-amethylamine metabolic process +
                                                is-aphenylethylamine metabolic process +
                                                is-aphosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine
                                                is-aphosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline
                                                is-aphosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine
                                                is-aprimary amino compound biosynthetic process +
                                                is-aprimary amino compound catabolic process +
                                                is-aserotonin metabolic process [GO:0042428] (12 genes, 13 annotations)
                                                        is-aserotonin biosynthetic process +
                                                        is-aserotonin catabolic process


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory