Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF169
  • Mouse genes Rnf169
  • Rat genes Rnf169
  • Zfish genes rnf169
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf169

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	RNF169	IDA		Human	PMID:22492721
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	RNF169	IDA		Human	PMID:22733822
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	RNF169	IDA		Human	PMID:22742833
Molecular Function	GO:0031491	nucleosome binding	RNF169	IDA		Human	PMID:22742833
Molecular Function	GO:0005515	protein binding	RNF169	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF169	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF169	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF169	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF169	IPI	UniProtKB:Q96ED9-2	Human	PMID:32296183
Molecular Function	GO:0061649	ubiquitin modification-dependent histone binding	RNF169	IDA		Human	PMID:22492721
Cellular Component	GO:0005829	cytosol	RNF169	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	RNF169	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	RNF169	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RNF169	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RNF169	IDA		Human	PMID:22492721
Cellular Component	GO:0005634	nucleus	RNF169	IDA		Human	PMID:22733822
Cellular Component	GO:0035861	site of double-strand break	RNF169	IDA		Human	PMID:22492721
Cellular Component	GO:0035861	site of double-strand break	RNF169	IDA		Human	PMID:22733822
Cellular Component	GO:0035861	site of double-strand break	RNF169	IDA		Human	PMID:22742833
Biological Process	GO:0006974	DNA damage response	RNF169	IMP		Human	PMID:22492721
Biological Process	GO:0006974	DNA damage response	RNF169	IDA		Human	PMID:22733822
Biological Process	GO:0000724	double-strand break repair via homologous recombination	RNF169	IDA		Human	PMID:22492721
Biological Process	GO:2000780	negative regulation of double-strand break repair	RNF169	IMP		Human	PMID:22492721
Biological Process	GO:2000780	negative regulation of double-strand break repair	RNF169	IMP		Human	PMID:22733822
Biological Process	GO:2000780	negative regulation of double-strand break repair	RNF169	IDA		Human	PMID:22742833

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern