Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNASE1
  • Mouse genes Rnase1
  • Rat genes Rnase1,Rnase1l1,Rnase1l2
  • Zfish genes rnasel2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnase1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RNASE1	IPI	UniProtKB:P13489	Human	PMID:17350650
Molecular Function	GO:0005515	protein binding	RNASE1	IPI	UniProtKB:P13489	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RNASE1	IPI	UniProtKB:P13489	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	RNASE1	IPI	UniProtKB:Q9C029	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNASE1	IPI	UniProtKB:P13489	Human	PMID:32814053
Molecular Function	GO:0004540	RNA nuclease activity	RNASE1	IDA		Human	PMID:9826755
Molecular Function	GO:0004540	RNA nuclease activity	rnasel2	IDA		Zfish	PMID:16861230
Molecular Function	GO:0004540	RNA nuclease activity	rnasel2	IDA		Zfish	PMID:17347156
Cellular Component	GO:0070062	extracellular exosome	RNASE1	HDA		Human	PMID:23533145
Biological Process	GO:0001525	angiogenesis	rnasel2	IDA		Zfish	PMID:16861230
Biological Process	GO:0050829	defense response to Gram-negative bacterium	rnasel2	IDA		Zfish	PMID:21050179
Biological Process	GO:0050829	defense response to Gram-negative bacterium	rnasel2	IDA		Zfish	PMID:17347156
Biological Process	GO:0050830	defense response to Gram-positive bacterium	rnasel2	IDA		Zfish	PMID:21050179
Biological Process	GO:0050830	defense response to Gram-positive bacterium	rnasel2	IDA		Zfish	PMID:17347156
Biological Process	GO:0009617	response to bacterium	Rnase1	IEP		Mouse	PMID:23012479
Biological Process	GO:0090501	RNA phosphodiester bond hydrolysis	RNASE1	IDA		Human	PMID:9826755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern