Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RFTN1
  • Mouse genes Rftn1
  • Rat genes Rftn1
  • Zfish genes rftn1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rftn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003725	double-stranded RNA binding	RFTN1	IDA		Human	PMID:21266579
Cellular Component	GO:0005737	cytoplasm	RFTN1	IDA		Human	PMID:21266579
Cellular Component	GO:0005768	endosome	RFTN1	IDA		Human	PMID:21266579
Cellular Component	GO:0070062	extracellular exosome	RFTN1	HDA		Human	PMID:20458337
Cellular Component	GO:0045121	membrane raft	RFTN1	IDA		Human	PMID:12805216
Cellular Component	GO:0045121	membrane raft	RFTN1	IDA		Human	PMID:21955986
Cellular Component	GO:0005886	plasma membrane	RFTN1	IDA		Human	PMID:12805216
Cellular Component	GO:0005886	plasma membrane	RFTN1	IDA		Human	PMID:21266579
Cellular Component	GO:0032991	protein-containing complex	RFTN1	IDA		Human	PMID:21266579
Biological Process	GO:0050853	B cell receptor signaling pathway	RFTN1	IMP		Human	PMID:12805216
Biological Process	GO:0033227	dsRNA transport	RFTN1	IMP		Human	PMID:21266579
Biological Process	GO:0001765	membrane raft assembly	RFTN1	IMP		Human	PMID:12805216
Biological Process	GO:0040010	positive regulation of growth rate	RFTN1	IMP		Human	PMID:12805216
Biological Process	GO:0032740	positive regulation of interleukin-17 production	Rftn1	IMP		Mouse	MGI:MGI:3850290|PMID:19414744
Biological Process	GO:1903044	protein localization to membrane raft	Rftn1	IMP		Mouse	MGI:MGI:3850290|PMID:19414744
Biological Process	GO:0032596	protein transport into membrane raft	Rftn1	IMP		Mouse	MGI:MGI:3850290|PMID:19414744
Biological Process	GO:0043330	response to exogenous dsRNA	RFTN1	IMP		Human	PMID:21266579
Biological Process	GO:0002457	T cell antigen processing and presentation	Rftn1	IMP		Mouse	MGI:MGI:3850290|PMID:19414744
Biological Process	GO:0050852	T cell receptor signaling pathway	Rftn1	IMP		Mouse	MGI:MGI:3850290|PMID:19414744
Biological Process	GO:0034138	toll-like receptor 3 signaling pathway	RFTN1	IMP		Human	PMID:21266579

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern