Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RFLNB
  • Mouse genes Rflnb
  • Rat genes Rflnb
  • Zfish genes rflnb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rflnb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031005	filamin binding	RFLNB	IDA		Human	PMID:21709252
Cellular Component	GO:0015629	actin cytoskeleton	Rflnb	IDA		Mouse	PMID:21709252
Cellular Component	GO:0032432	actin filament bundle	Rflnb	IDA		Mouse	PMID:24436304
Biological Process	GO:0030036	actin cytoskeleton organization	Rflnb	IMP		Mouse	PMID:21709252
Biological Process	GO:0030036	actin cytoskeleton organization	Rflnb	IGI	MGI:MGI:95556	Mouse	PMID:21709252
Biological Process	GO:0061572	actin filament bundle organization	Rflnb	IGI	MGI:MGI:1920371	Mouse	PMID:24436304
Biological Process	GO:0001837	epithelial to mesenchymal transition	Rflnb	IGI	MGI:MGI:95556	Mouse	PMID:21709252
Biological Process	GO:1900158	negative regulation of bone mineralization involved in bone maturation	Rflnb	IGI	MGI:MGI:1920371	Mouse	PMID:24436304
Biological Process	GO:0061182	negative regulation of chondrocyte development	Rflnb	IGI	MGI:MGI:1920371	Mouse	PMID:24436304
Biological Process	GO:0048705	skeletal system morphogenesis	Rflnb	IGI	MGI:MGI:1920371	Mouse	PMID:24436304

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern