Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RFC2
  • Mouse genes Rfc2
  • Rat genes Rfc2
  • Zfish genes rfc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rfc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003689	DNA clamp loader activity	RFC2	IDA		Human	PMID:12930902
Molecular Function	GO:0019899	enzyme binding	Rfc2	IPI	UniProtKB:Q0VGM9	Mouse	MGI:MGI:5522574|PMID:24115439
Molecular Function	GO:0005515	protein binding	RFC2	IPI	UniProtKB:P10644	Human	PMID:15655353
Molecular Function	GO:0005515	protein binding	RFC2	IPI	UniProtKB:P35249	Human	PMID:15655353
Molecular Function	GO:0005515	protein binding	RFC2	IPI	UniProtKB:P35251	Human	PMID:15655353
Molecular Function	GO:0005515	protein binding	RFC2	IPI	UniProtKB:Q96FC9	Human	PMID:18499658
Molecular Function	GO:0005515	protein binding	RFC2	IPI	UniProtKB:P35249	Human	PMID:9488738
Molecular Function	GO:0005515	protein binding	RFC2	IPI	UniProtKB:P35251	Human	PMID:9488738
Molecular Function	GO:0017116	single-stranded DNA helicase activity	RFC2	IDA		Human	PMID:12930902
Cellular Component	GO:0031390	Ctf18 RFC-like complex	RFC2	IDA		Human	PMID:12930902
Cellular Component	GO:0005663	DNA replication factor C complex	RFC2	IDA		Human	PMID:9488738
Biological Process	GO:1900264	positive regulation of DNA-directed DNA polymerase activity	RFC2	IDA		Human	PMID:12930902

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern