Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RDH11
  • Mouse genes Rdh11
  • Rat genes Rdh11
  • Zfish genes rdh12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rdh11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033721	aldehyde dehydrogenase (NADP+) activity	Rdh11	IDA		Mouse	MGI:MGI:2673050|PMID:12807874
Molecular Function	GO:0052650	NADP-retinol dehydrogenase activity	RDH11	IDA		Human	PMID:12226107
Molecular Function	GO:0052650	NADP-retinol dehydrogenase activity	RDH11	IDA		Human	PMID:12807874
Molecular Function	GO:0005515	protein binding	RDH11	IPI	UniProtKB:O60613	Human	PMID:29410696
Cellular Component	GO:0005789	endoplasmic reticulum membrane	RDH11	IDA		Human	PMID:12807874
Cellular Component	GO:0001917	photoreceptor inner segment	Rdh11	IDA		Mouse	PMID:15790565
Biological Process	GO:0016062	adaptation of rhodopsin mediated signaling	Rdh11	IMP	MGI:MGI:3586379	Mouse	PMID:15790565
Biological Process	GO:0110095	cellular detoxification of aldehyde	RDH11	IDA		Human	PMID:12807874
Biological Process	GO:0110095	cellular detoxification of aldehyde	Rdh11	IDA		Mouse	MGI:MGI:2673050|PMID:12807874
Biological Process	GO:0042574	retinal metabolic process	RDH11	IDA		Human	PMID:12807874
Biological Process	GO:0001523	retinoid metabolic process	RDH11	IDA		Human	PMID:12226107
Biological Process	GO:0042572	retinol metabolic process	Rdh11	IMP		Mouse	MGI:MGI:6189614|PMID:29567832
Biological Process	GO:0007601	visual perception	Rdh11	IMP		Mouse	MGI:MGI:3584215|PMID:15790565

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern