Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RBBP6
  • Mouse genes Rbbp6
  • Rat genes Rbbp6
  • Zfish genes rbbp6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rbbp6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RBBP6	IPI	UniProtKB:Q16629	Human	PMID:18624398
Molecular Function	GO:0005515	protein binding	RBBP6	IPI	UniProtKB:P67809	Human	PMID:18851979
Molecular Function	GO:0005515	protein binding	RBBP6	IPI	UniProtKB:Q8NAP3	Human	PMID:24726359
Molecular Function	GO:0005515	protein binding	RBBP6	IPI	UniProtKB:P46937	Human	PMID:35044719
Molecular Function	GO:0019901	protein kinase binding	RBBP6	IPI	UniProtKB:Q9HC98	Human	PMID:20873783
Molecular Function	GO:0003723	RNA binding	RBBP6	HDA		Human	PMID:22681889
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RBBP6	IMP		Human	PMID:24726359
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RBBP6	IDA		Human	PMID:18851979
Cellular Component	GO:0005813	centrosome	RBBP6	IDA		Human	PMID:20873783
Cellular Component	GO:0016607	nuclear speck	RBBP6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	RBBP6	IDA		Human	PMID:20873783
Biological Process	GO:0006974	DNA damage response	RBBP6	IMP		Human	PMID:24726359
Biological Process	GO:0048568	embryonic organ development	Rbbp6	IGI	MGI:MGI:98834	Mouse	PMID:17470788
Biological Process	GO:0001701	in utero embryonic development	Rbbp6	IMP	MGI:MGI:3711066	Mouse	PMID:17470788
Biological Process	GO:0035264	multicellular organism growth	Rbbp6	IMP	MGI:MGI:3711066	Mouse	PMID:17470788
Biological Process	GO:0006275	regulation of DNA replication	RBBP6	IMP		Human	PMID:24726359
Biological Process	GO:0061053	somite development	Rbbp6	IMP	MGI:MGI:3711066	Mouse	PMID:17470788
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RBBP6	IDA		Human	PMID:18851979
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RBBP6	IMP		Human	PMID:24726359
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Rbbp6	IMP		Mouse	MGI:MGI:5688821|PMID:24726359

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern