Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB22A
  • Mouse genes Rab22a
  • Rat genes Rab22a
  • Zfish genes rab22a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab22a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RAB22A	IDA		Human	PMID:20937701
Molecular Function	GO:0005525	GTP binding	RAB22A	IMP		Human	PMID:24466322
Molecular Function	GO:0005525	GTP binding	Rab22a	IDA		Mouse	MGI:MGI:4399023|PMID:16034420
Molecular Function	GO:0003924	GTPase activity	RAB22A	IMP		Human	PMID:24466322
Molecular Function	GO:0003924	GTPase activity	Rab22a	IDA		Mouse	MGI:MGI:4399023|PMID:16034420
Molecular Function	GO:0005515	protein binding	RAB22A	IPI	UniProtKB:Q15075	Human	PMID:11870209
Molecular Function	GO:0005515	protein binding	RAB22A	IPI	UniProtKB:Q8NEU8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RAB22A	IPI	UniProtKB:Q8NEU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAB22A	IPI	UniProtKB:Q8NEU8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RAB22A	IPI	UniProtKB:Q60I27	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB22A	IPI	UniProtKB:Q8NEU8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rab22a	IPI	UniProtKB:Q9H1K0	Mouse	MGI:MGI:4399023|PMID:16034420
Cellular Component	GO:0015629	actin cytoskeleton	Rab22a	IDA		Mouse	PMID:21419809
Cellular Component	GO:0005769	early endosome	RAB22A	IDA		Human	PMID:11870209
Cellular Component	GO:0070062	extracellular exosome	RAB22A	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RAB22A	HDA		Human	PMID:19199708
Cellular Component	GO:0045335	phagocytic vesicle	RAB22A	IDA		Human	PMID:21255211
Cellular Component	GO:0005886	plasma membrane	RAB22A	IDA		Human	PMID:11870209
Biological Process	GO:0006897	endocytosis	RAB22A	IDA		Human	PMID:11870209
Biological Process	GO:0007032	endosome organization	RAB22A	IEP		Human	PMID:11870209
Biological Process	GO:0097494	regulation of vesicle size	RAB22A	IMP		Human	PMID:24466322

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern