Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTTG1,PTTG2,PTTG3P
  • Mouse genes Pttg1
  • Rat genes Pttg1
  • Zfish genes pttg1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pttg1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004869	cysteine-type endopeptidase inhibitor activity	Pttg1	IDA		Mouse	PMID:14561405
Molecular Function	GO:0031072	heat shock protein binding	Pttg1	IPI	RGD:1349519	Rat	PMID:9915854|RGD:2303787
Molecular Function	GO:0140677	molecular function activator activity	PTTG1	EXP		Human	PMID:15929994
Molecular Function	GO:0005515	protein binding	PTTG1	IPI	UniProtKB:Q14674	Human	PMID:12194817
Molecular Function	GO:0005515	protein binding	PTTG1	IPI	UniProtKB:Q14145	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Pttg1	IPI	RGD:621024|RGD:620942	Rat	PMID:9915854|RGD:2303787
Molecular Function	GO:0043022	ribosome binding	Pttg1	IPI	RGD:733640	Rat	PMID:9915854|RGD:2303787
Cellular Component	GO:0005737	cytoplasm	Pttg1	IDA		Mouse	PMID:17325031
Cellular Component	GO:0005829	cytosol	PTTG1	IDA		Human	PMID:9811450
Cellular Component	GO:0005634	nucleus	PTTG1	IDA		Human	PMID:9811450
Cellular Component	GO:0005634	nucleus	Pttg1	IDA		Mouse	PMID:17325031
Biological Process	GO:0007059	chromosome segregation	Pttg1	IGI	MGI:MGI:2146156	Mouse	PMID:16533945
Biological Process	GO:0045143	homologous chromosome segregation	Pttg1	IDA		Mouse	PMID:14561405
Biological Process	GO:0007064	mitotic sister chromatid cohesion	Pttg1	IGI	MGI:MGI:1859866	Mouse	PMID:17325031
Biological Process	GO:0008285	negative regulation of cell population proliferation	Pttg1	IMP		Rat	PMID:9092795|RGD:68295
Biological Process	GO:0001558	regulation of cell growth	Pttg1	IMP		Rat	PMID:9092795|RGD:68295

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern