Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTS
  • Mouse genes Pts
  • Rat genes Pts
  • Zfish genes pts
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pts

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003874	6-pyruvoyltetrahydropterin synthase activity	Pts	IDA		Mouse	PMID:9894812
Molecular Function	GO:0003874	6-pyruvoyltetrahydropterin synthase activity	Pts	IDA		Rat	PMID:1939130|RGD:68294
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:16169070
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:24599843
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:25502805
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:25910212
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	PTS	IPI	UniProtKB:Q03393	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Pts	IPI	PR:Q9R1Z7	Mouse	PMID:9894812
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:P51116	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:Q96HA8	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:P38432	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:Q8TBB1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:Q9P2Z0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:O00560	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:P51116	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:Q96HA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:Q96CW1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTS	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	PTS	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005739	mitochondrion	PTS	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005739	mitochondrion	Pts	HDA		Mouse	PMID:18614015
Biological Process	GO:0006729	tetrahydrobiopterin biosynthetic process	Pts	IDA		Mouse	PMID:9894812

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern