Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPRB
  • Mouse genes Ptprb
  • Rat genes Ptprb
  • Zfish genes ptprb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptprb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	PTPRB	IPI	UniProtKB:P33151	Human	PMID:28926625
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P27361	Human	PMID:12840032
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P10912	Human	PMID:12907755
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P08581	Human	PMID:16101282
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P00533	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P04626	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P10912	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P27361	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:Q02763	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:Q02763	Human	PMID:19451274
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P00533	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	PTPRB	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Ptprb	IPI	UniProtKB:P55284	Mouse	MGI:MGI:4419091|PMID:12234928
Molecular Function	GO:0005515	protein binding	Ptprb	IPI	UniProtKB:Q02858	Mouse	MGI:MGI:4412467|PMID:10557082
Cellular Component	GO:0043235	receptor complex	PTPRB	IDA		Human	PMID:23382219
Biological Process	GO:0001525	angiogenesis	Ptprb	IDA		Mouse	MGI:MGI:4412431|PMID:19451274
Biological Process	GO:0001525	angiogenesis	Ptprb	IMP		Mouse	MGI:MGI:3759922|PMID:16514057
Biological Process	GO:0001525	angiogenesis	Ptprb	IMP		Mouse	MGI:MGI:3760182|PMID:17360632
Biological Process	GO:0001568	blood vessel development	ptprb	IMP	ZFIN:ZDB-MRPHLNO-130128-1	Zfish	PMID:23251467
Biological Process	GO:0001568	blood vessel development	ptprb	IMP	ZFIN:ZDB-MRPHLNO-130128-2	Zfish	PMID:23251467
Biological Process	GO:0016311	dephosphorylation	PTPRB	IDA		Human	PMID:19116766
Biological Process	GO:0016311	dephosphorylation	PTPRB	IDA		Human	PMID:19136612
Biological Process	GO:0016311	dephosphorylation	Ptprb	IDA		Mouse	MGI:MGI:4412467|PMID:10557082
Biological Process	GO:0016311	dephosphorylation	Ptprb	IDA		Mouse	MGI:MGI:4419091|PMID:12234928
Biological Process	GO:0008347	glial cell migration	Ptprb	IMP		Rat	PMID:14692702|RGD:151660507
Biological Process	GO:1990264	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	Ptprb	IDA		Mouse	MGI:MGI:6379079|PMID:26063811

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern