Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPN23
  • Mouse genes Ptpn23
  • Rat genes Ptpn23
  • Zfish genes ptpn23a,ptpn23b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpn23

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:O75340	Human	PMID:17174262
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q99816	Human	PMID:17174262
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q99962	Human	PMID:17174262
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q9H444	Human	PMID:17174262
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q9H444	Human	PMID:18434552
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q05397	Human	PMID:18835089
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:O89100	Human	PMID:19523899
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:P62993	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:O75791	Human	PMID:21179510
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:P62993	Human	PMID:21179510
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:P12830	Human	PMID:21724833
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:P35222	Human	PMID:21724833
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:P25788	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q53EZ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:O75791	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:P62993	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q7Z3S9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTPN23	IPI	UniProtKB:Q96LK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ptpn23	IPI	UniProtKB:O89100	Mouse	MGI:MGI:5512953|PMID:19523899
Molecular Function	GO:0019901	protein kinase binding	PTPN23	IPI	UniProtKB:P12931	Human	PMID:21724833
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPN23	IMP		Human	PMID:21724833
Cellular Component	GO:0036064	ciliary basal body	PTPN23	IDA		Human	PMID:20393563
Cellular Component	GO:0005737	cytoplasm	PTPN23	IDA		Human	PMID:21179510
Cellular Component	GO:0005769	early endosome	PTPN23	IDA		Human	PMID:21757351
Cellular Component	GO:0005768	endosome	PTPN23	IDA		Human	PMID:21179510
Cellular Component	GO:0070062	extracellular exosome	PTPN23	HDA		Human	PMID:19056867
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PTPN23	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	PTPN23	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PTPN23	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PTPN23	IDA		Human	PMID:21179510
Biological Process	GO:0060271	cilium assembly	PTPN23	IMP		Human	PMID:20393563
Biological Process	GO:0045022	early endosome to late endosome transport	PTPN23	IMP		Human	PMID:24821423
Biological Process	GO:0032456	endocytic recycling	PTPN23	IMP		Human	PMID:24821423
Biological Process	GO:0010633	negative regulation of epithelial cell migration	PTPN23	IMP		Human	PMID:21724833
Biological Process	GO:1903393	positive regulation of adherens junction organization	PTPN23	IMP		Human	PMID:21724833
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	PTPN23	IMP		Human	PMID:21724833
Biological Process	GO:1903387	positive regulation of homophilic cell adhesion	PTPN23	IMP		Human	PMID:21724833
Biological Process	GO:0061357	positive regulation of Wnt protein secretion	PTPN23	IMP		Human	PMID:24821423
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	PTPN23	IMP		Human	PMID:21757351

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern