Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTGES2
  • Mouse genes Ptges2
  • Rat genes Ptges2
  • Zfish genes ptgesl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptges2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Ptges2	IDA		Mouse	PMID:12050152
Molecular Function	GO:0016829	lyase activity	PTGES2	IDA		Human	PMID:17585783
Molecular Function	GO:0050220	prostaglandin-E synthase activity	PTGES2	IDA		Human	PMID:12804604
Molecular Function	GO:0005515	protein binding	PTGES2	IPI	UniProtKB:Q5VU69	Human	PMID:25416956
Cellular Component	GO:0005829	cytosol	PTGES2	IDA		Human	PMID:12835322
Cellular Component	GO:0005829	cytosol	Ptges2	IDA		Mouse	PMID:12050152
Cellular Component	GO:0000139	Golgi membrane	PTGES2	IDA		Human	PMID:12835322
Cellular Component	GO:0005739	mitochondrion	PTGES2	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005739	mitochondrion	PTGES2	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	Ptges2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005634	nucleus	Ptges2	IDA		Mouse	PMID:12050152
Biological Process	GO:0006629	lipid metabolic process	PTGES2	IDA		Human	PMID:17585783
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Ptges2	IDA		Mouse	PMID:12050152
Biological Process	GO:0046903	secretion	Ptges2	IDA		Mouse	PMID:16217040

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern