| GO term: | lyase activity |
| Synonym: | other lyase activity |
| GO id: | GO:0016829 |
| Definition: | Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. |
| Comments | Note that enzymes of class EC:4.99.-.- should also be annotated to this term. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activitycatalysis of free radical formation +cyclase activity +deaminase activity +demethylase activity +first spliceosomal transesterification activityglycogen debranching enzyme activity +glyoxalase III activityhydrolase activity +integrase activity +isomerase activity +ligase activity +lyase activity [GO:0016829] (161 genes, 412 annotations)2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activityalkylmercury lyase activitycarbon phosphorus lyase activitycarbon-carbon lyase activity +carbon-halide lyase activity +carbon-nitrogen lyase activity +carbon-oxygen lyase activity +carbon-sulfur lyase activity +cobalt-precorrin-5A acetaldehyde-lyase activityferrochelatase activity +indoleacetaldoxime dehydratase activityphosphorus-oxygen lyase activity +sirohydrochlorin cobaltochelatase activityMo-molybdopterin cofactor sulfurase activityMo-molybdopterin synthase activityN-ethylammeline chlorohydrolase activityoxidoreductase activity +phenylacetaldehyde synthase activityphytoene synthase activityquinolinate synthetase A activityradical SAM enzyme activity +recombinase activitysecond spliceosomal transesterification activitysite-specific recombinase activity +site-specific telomere resolvase activitysmall protein activating enzyme activity +transferase activity +transposase activityUDP-L-rhamnose synthase activityversicolorin B synthase activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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