Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PROM2
  • Mouse genes Prom2
  • Rat genes Prom2
  • Zfish genes prom2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prom2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Molecular Function	GO:0005515	protein binding	PROM2	IPI	UniProtKB:Q86WK6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PROM2	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Cellular Component	GO:0042995	cell projection	PROM2	IDA		Human	PMID:23583380
Cellular Component	GO:0009986	cell surface	Prom2	IDA		Mouse	MGI:MGI:4938266|PMID:17109118
Cellular Component	GO:0009986	cell surface	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Cellular Component	GO:0005929	cilium	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Cellular Component	GO:0031410	cytoplasmic vesicle	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Cellular Component	GO:0070062	extracellular exosome	PROM2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PROM2	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PROM2	HDA		Human	PMID:23533145
Cellular Component	GO:0045121	membrane raft	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Cellular Component	GO:0044393	microspike	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Cellular Component	GO:0005902	microvillus	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Cellular Component	GO:0005886	plasma membrane	Prom2	IDA		Mouse	PMID:12514187
Cellular Component	GO:0005886	plasma membrane	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Cellular Component	GO:0071914	prominosome	Prom2	IDA		Mouse	MGI:MGI:4938266|PMID:17109118
Cellular Component	GO:0071914	prominosome	Prom2	IDA		Rat	PMID:17109118|RGD:8554554
Biological Process	GO:2001287	negative regulation of caveolin-mediated endocytosis	PROM2	IDA		Human	PMID:23583380
Biological Process	GO:0048550	negative regulation of pinocytosis	PROM2	IDA		Human	PMID:23583380
Biological Process	GO:0031346	positive regulation of cell projection organization	PROM2	IDA		Human	PMID:23583380
Biological Process	GO:0001934	positive regulation of protein phosphorylation	PROM2	IDA		Human	PMID:23583380
Biological Process	GO:0043087	regulation of GTPase activity	PROM2	IDA		Human	PMID:23583380

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern