Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRODH
  • Mouse genes Prodh
  • Rat genes Prodh
  • Zfish genes prodha,prodhb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prodh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Prodh	IMP		Rat	PMID:8373828|RGD:1599203
Molecular Function	GO:0071949	FAD binding	PRODH	IDA		Human	PMID:15662599
Molecular Function	GO:0004657	proline dehydrogenase activity	PRODH	EXP		Human	PMID:15662599
Molecular Function	GO:0004657	proline dehydrogenase activity	PRODH	IDA		Human	PMID:15662599
Molecular Function	GO:0004657	proline dehydrogenase activity	Prodh	IMP		Rat	PMID:8373828|RGD:1599203
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PRODH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005743	mitochondrial inner membrane	Prodh	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005739	mitochondrion	PRODH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Prodh	IDA		Mouse	PMID:18775783
Cellular Component	GO:0005739	mitochondrion	Prodh	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Prodh	IDA		Rat	PMID:8373828|RGD:1599203
Cellular Component	GO:0005654	nucleoplasm	PRODH	IDA		Human	GO_REF:0000052
Biological Process	GO:0010942	positive regulation of cell death	PRODH	IDA		Human	PMID:23743200

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern