Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKX,PRKY
  • Mouse genes Prkx
  • Rat genes Prkx
  • Zfish genes prkx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004691	cAMP-dependent protein kinase activity	PRKX	IDA		Human	PMID:10026146
Molecular Function	GO:0004691	cAMP-dependent protein kinase activity	PRKX	IDA		Human	PMID:17980165
Molecular Function	GO:0005515	protein binding	PRKX	IPI	UniProtKB:O43541	Human	PMID:16491121
Molecular Function	GO:0005515	protein binding	PRKX	IPI	UniProtKB:P10644	Human	PMID:16491121
Molecular Function	GO:0005515	protein binding	PRKX	IPI	UniProtKB:Q92917	Human	PMID:16491121
Molecular Function	GO:0005515	protein binding	PRKX	IPI	UniProtKB:P98161	Human	PMID:17980165
Molecular Function	GO:0005515	protein binding	PRKX	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	PRKX	IPI	UniProtKB:P08238	Human	PMID:32707033
Cellular Component	GO:0005737	cytoplasm	PRKX	IDA		Human	PMID:10026146
Cellular Component	GO:0005737	cytoplasm	PRKX	IDA		Human	PMID:21684272
Cellular Component	GO:0005737	cytoplasm	Prkx	IDA		Mouse	MGI:MGI:5294507|PMID:21684272
Cellular Component	GO:0005654	nucleoplasm	PRKX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PRKX	IDA		Human	PMID:10026146
Cellular Component	GO:0005634	nucleus	PRKX	IDA		Human	PMID:16491121
Cellular Component	GO:0005634	nucleus	PRKX	IDA		Human	PMID:21684272
Cellular Component	GO:0005634	nucleus	Prkx	IDA		Mouse	MGI:MGI:5294507|PMID:21684272
Biological Process	GO:0001525	angiogenesis	PRKX	IMP		Human	PMID:21684272
Biological Process	GO:0001525	angiogenesis	Prkx	IMP		Mouse	MGI:MGI:5294507|PMID:21684272
Biological Process	GO:0007155	cell adhesion	PRKX	IMP		Human	PMID:21684272
Biological Process	GO:0007155	cell adhesion	Prkx	IMP		Mouse	MGI:MGI:5294507|PMID:21684272
Biological Process	GO:0031589	cell-substrate adhesion	PRKX	IMP		Human	PMID:16491121
Biological Process	GO:0043542	endothelial cell migration	PRKX	IMP		Human	PMID:21684272
Biological Process	GO:0001935	endothelial cell proliferation	PRKX	IMP		Human	PMID:21684272
Biological Process	GO:0001935	endothelial cell proliferation	Prkx	IMP		Mouse	MGI:MGI:5294507|PMID:21684272
Biological Process	GO:0060562	epithelial tube morphogenesis	PRKX	IDA		Human	PMID:17980165
Biological Process	GO:0060993	kidney morphogenesis	PRKX	IDA		Human	PMID:17980165
Biological Process	GO:0030099	myeloid cell differentiation	PRKX	IDA		Human	PMID:9860982
Biological Process	GO:0018105	peptidyl-serine phosphorylation	PRKX	IDA		Human	PMID:16491121
Biological Process	GO:0046777	protein autophosphorylation	PRKX	IDA		Human	PMID:10026146
Biological Process	GO:0046777	protein autophosphorylation	PRKX	IDA		Human	PMID:16491121
Biological Process	GO:0030155	regulation of cell adhesion	PRKX	IDA		Human	PMID:17980165
Biological Process	GO:0030334	regulation of cell migration	PRKX	IDA		Human	PMID:17980165
Biological Process	GO:2000696	regulation of epithelial cell differentiation involved in kidney development	PRKX	IDA		Human	PMID:17980165

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern