Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKRIP1
  • Mouse genes Prkrip1
  • Rat genes Prkrip1
  • Zfish genes prkrip1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkrip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003725	double-stranded RNA binding	Prkrip1	IDA		Mouse	PMID:12679338
Molecular Function	GO:0005515	protein binding	PRKRIP1	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PRKRIP1	IPI	UniProtKB:Q8NHQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Prkrip1	IPI	PR:Q9JMB0	Mouse	PMID:12679338
Molecular Function	GO:0019901	protein kinase binding	Prkrip1	IDA		Mouse	PMID:12679338
Molecular Function	GO:0004860	protein kinase inhibitor activity	Prkrip1	IDA		Mouse	PMID:12679338
Cellular Component	GO:0070062	extracellular exosome	PRKRIP1	HDA		Human	PMID:19056867
Cellular Component	GO:0005730	nucleolus	Prkrip1	IDA		Mouse	PMID:12679338
Biological Process	GO:0042326	negative regulation of phosphorylation	Prkrip1	IDA		Mouse	PMID:12679338
Biological Process	GO:0006469	negative regulation of protein kinase activity	Prkrip1	IDA		Mouse	PMID:12679338
Biological Process	GO:0003014	renal system process	PRKRIP1	IDA		Human	PMID:21183621

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern