Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRKAB1
  • Mouse genes Prkab1
  • Rat genes Prkab1
  • Zfish genes prkab1a,prkab1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prkab1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q13131	Human	PMID:16306228
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q8TF40	Human	PMID:17028174
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q9P278	Human	PMID:18403135
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:O70302	Human	PMID:18480843
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54619	Human	PMID:18480843
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q13131	Human	PMID:18480843
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P62993	Human	PMID:18624398
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54619	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54646	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q13131	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:O75385	Human	PMID:21072212
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54619	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54619	Human	PMID:22363791
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q13131	Human	PMID:22363791
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q13131	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:O75385	Human	PMID:25686248
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q13131	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54619	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54646	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q9Y484	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54619	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:P54646	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PRKAB1	IPI	UniProtKB:Q13131	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Prkab1	IPI	RefSeq:NP_001074795	Mouse	PMID:15886229
Molecular Function	GO:0005515	protein binding	Prkab1	IPI	RGD:3388	Rat	PMID:8626596|RGD:729494
Molecular Function	GO:0004672	protein kinase activity	PRKAB1	IDA		Human	PMID:17028174
Molecular Function	GO:0019901	protein kinase binding	Prkab1	IPI	RGD:3387	Rat	PMID:15695819|RGD:1600470
Molecular Function	GO:0019901	protein kinase binding	Prkab1	IPI	RGD:3387	Rat	PMID:16648175|RGD:1600447
Molecular Function	GO:0019901	protein kinase binding	Prkab1	IPI	RGD:620893	Rat	PMID:16648175|RGD:1600447
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	PRKAB1	IPI		Human	PMID:29480465
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	PRKAB1	IPI		Human	PMID:9693118
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	Prkab1	IDA		Rat	PMID:16648175|RGD:1600447
Cellular Component	GO:0005634	nucleus	PRKAB1	IDA		Human	PMID:9693118
Cellular Component	GO:0005634	nucleus	Prkab1	IDA		Mouse	PMID:10098881
Cellular Component	GO:0032991	protein-containing complex	Prkab1	IDA		Rat	PMID:14511394|RGD:1600691
Biological Process	GO:0031669	cellular response to nutrient levels	PRKAB1	IDA		Human	PMID:30478170
Biological Process	GO:0035878	nail development	Prkab1	IMP		Mouse	PMID:25340873
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Prkab1	IGI	UniProtKB:Q6PAM0	Mouse	MGI:MGI:6101081|PMID:27411013
Biological Process	GO:0010628	positive regulation of gene expression	PRKAB1	IDA		Human	PMID:17028174
Biological Process	GO:0006468	protein phosphorylation	PRKAB1	IDA		Human	PMID:17028174

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern