Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP1R15B
  • Mouse genes Ppp1r15b
  • Rat genes Ppp1r15b
  • Zfish genes ppp1r15b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp1r15b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPP1R15B	IPI	UniProtKB:P62136	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	PPP1R15B	IPI	UniProtKB:P62136	Human	PMID:21382349
Molecular Function	GO:0005515	protein binding	PPP1R15B	IPI	UniProtKB:P62136	Human	PMID:22321011
Molecular Function	GO:0005515	protein binding	PPP1R15B	IPI	UniProtKB:P36873	Human	PMID:26307080
Molecular Function	GO:0005515	protein binding	PPP1R15B	IPI	UniProtKB:P36873	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP1R15B	IPI	UniProtKB:P62136	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP1R15B	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0019888	protein phosphatase regulator activity	Ppp1r15b	IDA		Mouse	PMID:14638860
Cellular Component	GO:0000164	protein phosphatase type 1 complex	PPP1R15B	IDA		Human	PMID:26307080
Cellular Component	GO:0000164	protein phosphatase type 1 complex	Ppp1r15b	IDA		Mouse	MGI:MGI:5613475|PMID:16835242
Cellular Component	GO:0000164	protein phosphatase type 1 complex	Ppp1r15b	IDA		Mouse	PMID:14638860
Biological Process	GO:0006983	ER overload response	Ppp1r15b	IDA		Mouse	PMID:14638860
Biological Process	GO:0006983	ER overload response	Ppp1r15b	IMP		Mouse	PMID:14638860
Biological Process	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Ppp1r15b	IDA		Mouse	MGI:MGI:5613475|PMID:16835242
Biological Process	GO:0001933	negative regulation of protein phosphorylation	PPP1R15B	IMP		Human	PMID:26307080
Biological Process	GO:0070262	peptidyl-serine dephosphorylation	Ppp1r15b	IDA		Mouse	MGI:MGI:5613475|PMID:16835242
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Ppp1r15b	IMP		Mouse	PMID:14638860
Biological Process	GO:0042542	response to hydrogen peroxide	Ppp1r15b	IMP		Mouse	PMID:14638860
Biological Process	GO:0006979	response to oxidative stress	Ppp1r15b	IDA		Mouse	PMID:14638860
Biological Process	GO:0006979	response to oxidative stress	Ppp1r15b	IMP		Mouse	PMID:14638860

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern