Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPFIA1
  • Mouse genes Ppfia1
  • Rat genes Ppfia1
  • Zfish genes ppfia1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppfia1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:P19491	Human	PMID:11931740
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:P97879	Human	PMID:11931740
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:O15083	Human	PMID:12923177
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q8IUD2	Human	PMID:12923177
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q14738	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q9NS73	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q9NS73	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:O60941	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:P40222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:P51946	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q3B820	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q14738	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:O60941	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:P40222	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:P51946	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q14738	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q3B820	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:O60941	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:P40222	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:P51946	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q07002	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q13409-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q14241	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPFIA1	IPI	UniProtKB:Q15172	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ppfia1	IPI	PR:O08808	Mouse	PMID:22266902
Molecular Function	GO:0005515	protein binding	Ppfia1	IPI	PR:Q6PH08	Mouse	PMID:23791195
Molecular Function	GO:0005515	protein binding	Ppfia1	IPI	PR:O88952	Mouse	PMID:16186258
Cellular Component	GO:0030424	axon	Ppfia1	IDA		Rat	PMID:12522103|RGD:12911232
Cellular Component	GO:0005829	cytosol	PPFIA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030425	dendrite	Ppfia1	IDA		Rat	PMID:12522103|RGD:12911232
Cellular Component	GO:0005925	focal adhesion	PPFIA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Ppfia1	IDA		Rat	PMID:12629171|RGD:152995492
Cellular Component	GO:0032991	protein-containing complex	Ppfia1	IDA		Rat	PMID:12522103|RGD:12911232
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Ppfia1	IDA		Rat	PMID:11931740|RGD:619588
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Ppfia1	IMP		Rat	PMID:11931740|RGD:619588
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Ppfia1	IDA		Rat	PMID:17419996|RGD:14696670
Cellular Component	GO:0097444	spine apparatus	Ppfia1	IDA		Rat	PMID:17419996|RGD:14696670
Biological Process	GO:0007420	brain development	Ppfia1	IEP		Rat	PMID:12629171|RGD:152995492
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	PPFIA1	IMP		Human	PMID:22266902
Biological Process	GO:0051497	negative regulation of stress fiber assembly	PPFIA1	IMP		Human	PMID:22266902
Biological Process	GO:0051497	negative regulation of stress fiber assembly	Ppfia1	IDA		Mouse	PMID:22266902
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Ppfia1	IDA		Rat	PMID:11931740|RGD:619588
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Ppfia1	IMP		Rat	PMID:11931740|RGD:619588

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern