Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPEF2
  • Mouse genes Ppef2
  • Rat genes Ppef2
  • Zfish genes ppef2a,ppef2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppef2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030544	Hsp70 protein binding	PPEF2	IDA		Human	PMID:20674765
Molecular Function	GO:0051879	Hsp90 protein binding	PPEF2	IDA		Human	PMID:20674765
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	PPEF2	IPI	UniProtKB:Q99683	Human	PMID:20674765
Biological Process	GO:0043010	camera-type eye development	ppef2b	IMP	ZFIN:ZDB-MRPHLNO-200807-6	Zfish	PMID:31934309
Biological Process	GO:0043010	camera-type eye development	ppef2a	IMP	ZFIN:ZDB-MRPHLNO-200807-5	Zfish	PMID:31934309
Biological Process	GO:0043409	negative regulation of MAPK cascade	PPEF2	IDA		Human	PMID:20674765
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	PPEF2	IDA		Human	PMID:20674765

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern