Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POR
  • Mouse genes Por
  • Rat genes Por
  • Zfish genes pora,porb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Por

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	Por	IDA		Rat	PMID:16055078|RGD:4889840
Molecular Function	GO:0009055	electron transfer activity	Por	IDA		Rat	PMID:19171935|RGD:4889812
Molecular Function	GO:0019899	enzyme binding	Por	IPI	RGD:2458	Rat	PMID:11350928|RGD:2306635
Molecular Function	GO:0019899	enzyme binding	Por	IPI	UniProtKB:P06762	Rat	PMID:15516695|RGD:8554849
Molecular Function	GO:0019899	enzyme binding	Por	IPI	UniProtKB:P05177	Rat	PMID:15680923|RGD:8553304
Molecular Function	GO:0019899	enzyme binding	Por	IPI	UniProtKB:P05181	Rat	PMID:15680923|RGD:8553304
Molecular Function	GO:0019899	enzyme binding	Por	IPI	UniProtKB:P11509	Rat	PMID:15680923|RGD:8553304
Molecular Function	GO:0019899	enzyme binding	Por	IPI	UniProtKB:P33261	Rat	PMID:15680923|RGD:8553304
Molecular Function	GO:0019899	enzyme binding	Por	IMP		Rat	PMID:16928691|RGD:1599694
Molecular Function	GO:0019899	enzyme binding	Por	IPI	RGD:1317784	Rat	PMID:17446262|RGD:4889826
Molecular Function	GO:0019899	enzyme binding	Por	IDA		Rat	PMID:9774150|RGD:1599688
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	Por	IMP		Rat	PMID:16928691|RGD:1599694
Molecular Function	GO:0010181	FMN binding	Por	IMP		Rat	PMID:16928691|RGD:1599694
Molecular Function	GO:0016787	hydrolase activity	Por	IDA		Rat	PMID:16226717|RGD:4889838
Molecular Function	GO:0047726	iron-cytochrome-c reductase activity	Por	IDA		Rat	PMID:15823091|RGD:4889615
Molecular Function	GO:0050661	NADP binding	Por	IMP		Rat	PMID:16928691|RGD:1599694
Molecular Function	GO:0050661	NADP binding	Por	IDA		Rat	PMID:9774150|RGD:1599688
Molecular Function	GO:0003958	NADPH-hemoprotein reductase activity	POR	IDA		Human	PMID:10048323
Molecular Function	GO:0003958	NADPH-hemoprotein reductase activity	POR	IDA		Human	PMID:19448135
Molecular Function	GO:0003958	NADPH-hemoprotein reductase activity	POR	IDA		Human	PMID:2513880
Molecular Function	GO:0003958	NADPH-hemoprotein reductase activity	Por	IMP		Rat	PMID:16928691|RGD:1599694
Molecular Function	GO:0003958	NADPH-hemoprotein reductase activity	Por	IDA		Rat	PMID:19171935|RGD:4889812
Molecular Function	GO:0003958	NADPH-hemoprotein reductase activity	Por	IDA		Rat	PMID:9774150|RGD:1599688
Molecular Function	GO:0008941	nitric oxide dioxygenase activity	Por	IDA		Rat	PMID:19152507|RGD:2316786
Molecular Function	GO:0016491	oxidoreductase activity	Por	IMP	MGI:MGI:2159651	Mouse	PMID:11742006
Molecular Function	GO:0005515	protein binding	POR	IPI	UniProtKB:O00264	Human	PMID:21081644
Molecular Function	GO:0005515	protein binding	POR	IPI	UniProtKB:P00181	Human	PMID:21081644
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	POR	IDA		Human	PMID:9618440
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Por	IDA		Rat	PMID:9774150|RGD:1599688
Cellular Component	GO:0016020	membrane	POR	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Por	IDA		Rat	PMID:19152507|RGD:2316786
Cellular Component	GO:0005739	mitochondrion	Por	IDA		Rat	PMID:9774150|RGD:1599688
Biological Process	GO:0009437	carnitine metabolic process	Por	IEP		Rat	PMID:16616465|RGD:4889829
Biological Process	GO:0090346	cellular organofluorine metabolic process	POR	IDA		Human	PMID:19448135
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	Por	IEP		Rat	PMID:19077323|RGD:2316787
Biological Process	GO:0071371	cellular response to gonadotropin stimulus	Por	IEP		Rat	PMID:19077323|RGD:2316787
Biological Process	GO:0071375	cellular response to peptide hormone stimulus	Por	IEP		Rat	PMID:19077323|RGD:2316787
Biological Process	GO:0070988	demethylation	Por	IDA		Rat	PMID:19171935|RGD:4889812
Biological Process	GO:0022900	electron transport chain	POR	IDA		Human	PMID:10048323
Biological Process	GO:0022900	electron transport chain	POR	IDA		Human	PMID:2513880
Biological Process	GO:0019395	fatty acid oxidation	Por	IDA		Rat	PMID:17400174|RGD:4889827
Biological Process	GO:0009812	flavonoid metabolic process	Por	IEP		Rat	PMID:18803703|RGD:4889813
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	Por	IDA		Rat	PMID:18194664|RGD:4889819
Biological Process	GO:0043066	negative regulation of apoptotic process	Por	IMP		Rat	PMID:19264869|RGD:2316785
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Por	IMP		Rat	PMID:19264869|RGD:2316785
Biological Process	GO:0060192	negative regulation of lipase activity	Por	IDA		Rat	PMID:18801337|RGD:4889814
Biological Process	GO:0043602	nitrate catabolic process	Por	IDA		Rat	PMID:16527817|RGD:4889831
Biological Process	GO:0046210	nitric oxide catabolic process	Por	IDA		Rat	PMID:19152507|RGD:2316786
Biological Process	GO:0046210	nitric oxide catabolic process	Por	IMP		Rat	PMID:19152507|RGD:2316786
Biological Process	GO:0045542	positive regulation of cholesterol biosynthetic process	Por	IMP		Rat	PMID:19264869|RGD:2316785
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	Por	IMP		Rat	PMID:19264869|RGD:2316785
Biological Process	GO:0032770	positive regulation of monooxygenase activity	POR	IDA		Human	PMID:19448135
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Por	IMP		Rat	PMID:19264869|RGD:2316785
Biological Process	GO:0090031	positive regulation of steroid hormone biosynthetic process	Por	IDA		Rat	PMID:2495435|RGD:4889602
Biological Process	GO:0090181	regulation of cholesterol metabolic process	Por	IMP		Rat	PMID:19264869|RGD:2316785
Biological Process	GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	Por	IMP		Rat	PMID:19264869|RGD:2316785
Biological Process	GO:0071548	response to dexamethasone	Por	IDA		Rat	PMID:27856527|RGD:127285625
Biological Process	GO:0007584	response to nutrient	Por	IEP		Rat	PMID:17392395|RGD:4889828
Biological Process	GO:0009410	response to xenobiotic stimulus	Por	IEP		Rat	PMID:19265259|RGD:4889621

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern